Transfected cell immunoblot: extracts of COS cells transiently transfected with GFP-tagged CDY1, HA- and Flag- tagged CDYL1 and CDYL2 and untagged Kv2.1 plasmids and probed with N143/36 (left panel), anti-Flag (middle panel) and K89/34 (right panel) TC supe.
Testis-specific chromodomain protein Y 1 and Testis-specific chromodomain protein Y 2 are encoded by the genes CDY1 and CDY2A respectively, as well as the autosomal genes known as CDYL 1 and 2 (CDY-like). These protein products contain a chromodomain, involved in chromatin binding, and a histone acetyltransferase catalytic domain. These proteins are expressed ubiquitously in tissues. Diseases associated with CDYL include Chromosome 6Pter-P24 Deletion Syndrome.
CDY1 CDY1A; CDY1B
Fusion protein amino acids 6-66 (Chromo domain) of human CDY1 (also known as Testis-specific chromodomain protein Y 1, accession number Q9Y6F8); 100% identity with human CDY273% identity with human CDYL1 (44/60 amino acids identical); 51% identity with human CDYL2 (31/60 amino acids identical)
Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.