Transfected cell immunoblot: extracts of COS cells transiently transfected with GFP-tagged CDY1, HA- and Flag- tagged CDYL1 and CDYL2 and untagged Kv2.1 plasmids and probed with N143/36 (left panel), anti-Flag (middle panel) and K89/34 (right panel) TC supe.
Testis-specific chromodomain protein Y 1 and Testis-specific chromodomain protein Y 2 are encoded by the genes CDY1 and CDY2A respectively, as well as the autosomal genes known as CDYL 1 and 2 (CDY-like). These protein products contain a chromodomain, involved in chromatin binding, and a histone acetyltransferase catalytic domain. These proteins are expressed ubiquitously in tissues. Diseases associated with CDYL include Chromosome 6Pter-P24 Deletion Syndrome.
CDY1 CDY1A; CDY1B
Fusion protein amino acids 6-66 (Chromo domain) of human CDY1 (also known as Testis-specific chromodomain protein Y 1, accession number Q9Y6F8); 100% identity with human CDY273% identity with human CDYL1 (44/60 amino acids identical); 51% identity with human CDYL2 (31/60 amino acids identical)
Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Cross-reacts with CDYL1 and CDYL2
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
24 months from opening
Testis-specific chromodomain protein Y 1 (EC 18.104.22.168)
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