Anti-Cav1.3 Ca2+ Channel Antibody FL550 Conjugate (N38/8)

Name: Anti-Cav1.3 Ca2+ Channel Antibody FL550 Conjugate
Brand: NeuroMab
SKU: 75-080-FL550
Price: 460.0 USD
Availability: InStock

Our Anti-Cav1.3 Ca2+ channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N38/8. It detects human, mouse, and rat Cav1.3 Ca2+ channel, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Species Reactivity

Human, Mouse, Rat

Applications

ICC, IHC

Host Species

Mouse

Available Conjugates

Unconjugated

490

594

650

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Data Sheet

SKU: 75-080-FL550

Volume: 200 µL

Variant

Price:

$460.00

Quantity:

Product Details

Target

Cav1.3 Ca2+ channel

Target Description

Voltage-dependent L-type calcium channel subunit alpha-1D, or Cav1.3 calcium channel is a calcium channel encoded by the gene CACNA1D. It is a member of the L type voltage dependent calcium channel family. These calcium channels mediate the influx of calcium ions into a cell upon membrane polarization. Cav1.3 is expressed primarily in the membrane of the heart, brain (cerebral cortex, hippocampus, basal ganglia and thalamus). and pancreatic islets. Calcium channels are involved in many cell processes including muscle contraction, neurotransmitter release, gene expression, cell division and cell death. Diseases associated with Cav1.3 include Primary Aldosteronism, Seizures, Sinoatrial Node Dysfunction and Deafness.

Format

Purified by Protein A chromatography

Concentration

0.5 mg/mL

Clonality

Monoclonal

Clone

N38/8

Isotype

IgG1

Applications

ICC, IHC

Host Species

Mouse

Gene Name

Cacna1d Cach3 Cacn4 Cacnl1a2 Cchl1a2

Molecular Weight

>220 kDa

Antigen

Fusion protein amino acids 2025-2161 (C-terminus) of rat Cav1.3 (accession number P27732) produced recombinantly in E. Coli

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2939305

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL550 Ex: 550 nm, Em: 575 nm

Specificity

Does not cross-react with Cav1.2

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Voltage-dependent L-type calcium channel subunit alpha-1D (Calcium channel, L type, alpha-1 polypeptide, isoform 2) (Rat brain class D) (RBD) (Voltage-gated calcium channel subunit alpha Cav1.3)

UniProt Details

UniProt (Human): Q01668
UniProt (Immunogen Species): P27732

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Anti-Cav1.3 Ca2+ Channel Antibody FL550 Conjugate (N38/8)

SKU: 75-080-FL550

Product Details

Bulk Order Anti-Cav1.3 Ca2+ Channel Antibody FL550 Conjugate

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