Anti-C-reactive protein Antibody
Our Anti-C-reactive protein sheep polyclonal primary antibody detects human C-reactive protein, and is whole serum. It is validated for use in WB.
SKU: S-071-100
Product Details
C-reactive protein
C-reactive protein has several roles associated with host defence such as; promoting agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. It can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. COFACTOR: Binds 2 calcium ions per subunit. C-reactive protein exists as a homopentamer. Pentaxin (or Pentraxin) have a discoid arrangement of 5 non-covalently bound subunits. There are 2 alternatively spliced isoforms. C-reactive protein is found in plasma and its concentration increases greatly during acute phase response to tissue injury, infection or other inflammatory stimuli. It is induced by IL-1 and IL-6.
Whole serum
Polyclonal
Mixed
WB
Sheep
Human recombinant C-Reactive protein
Human
Human
Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material. After reconstitution keep aliquots at -20°C for a higher stability, and at 2-8°C with an appropriate antibacterial agent.
Lyophilized
Lyophilized with 0.01% Thimerosal
WB: 1:10000-1:100000
Unconjugated
It has been shown to be specific for C-reactive protein by WB. Human, other species have not yet been tested.
For research use only.
United States
12 months after date of receipt (unopened vial).
CRP; PTX1
25°C (ambient)