Calcium-activated potassium channel subunit beta-4, Potassium Calcium-Activated Channel Subfamily M Regulatory Beta Subunit 4 or BKBeta4 is encoded by the gene KCNMB4. BKbeta4 can bind to KCNMA1 to form a channel in the calcium activated large conductance (MaxiK channel) family. BKbeta4 acts to modulate the calcium sensitivity and gating kinetics of KCNMA1. It is expressed in brain and CNS.
IHC, IP, WB
Fusion protein amino acids 45-167 (entire extracellular domain) of mouse BKBeta4 (accession number Q9JIN6); Rat: 100% identity (123/123 amino acids identical); Human: 95% identity (117/123 amino acids identical)
Human, Mouse, Rat
Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
No cross-reactivity against BKBeta1, BKBeta2 or BKBeta3
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.