Anti-Beta4-Spectrin Antibody (N393/76)

from NeuroMab Datasheet
11 Citations

Available Conjugates

490
550
594
650

Primary Antibody
Human, Mouse, Rat
N393/76
ICC, IHC, WB
Mouse
Purified by Protein A chromatography
SPTBN4 KIAA1642 SPTBN3
>200 kDa

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Adult rat cerebral cortex immunohistochemistry.
Hippocampus immunohistochemistry with antigen retrieval via pepsin pretreatment showing axon initial segment and nodal staining.
Higher magnification of corpus callosum and CA1.
Immunoblot against extracts of COS cells transiently transfected with tagged Beta-spectrins or untagged Kv2.1 plasmid probed with N393/76 (left) or 19E10 (right) TC supe.
Immunocytochemistry for α1, α2, and β4 spectrin (cat. 75-377, 1:500) carried out in fixed and permeabilized DIV 21 primary cultured pHα2 mouse neurons. Image from publication CC-BY-4.0. PMID:36604600
Adult rat cerebral cortex immunohistochemistry.
Adult rat cerebral cortex immunohistochemistry.
Hippocampus immunohistochemistry with antigen retrieval via pepsin pretreatment showing axon initial segment and nodal staining.
Higher magnification of corpus callosum and CA1.
Immunoblot against extracts of COS cells transiently transfected with tagged Beta-spectrins or untagged Kv2.1 plasmid probed with N393/76 (left) or 19E10 (right) TC supe.
Immunocytochemistry for α1, α2, and β4 spectrin (cat. 75-377, 1:500) carried out in fixed and permeabilized DIV 21 primary cultured pHα2 mouse neurons. Image from publication CC-BY-4.0. PMID:36604600

Anti-Beta4-Spectrin Antibody
SKU: 75-377

Volume: 100 µL
1-2 business days
Price:
$361

Bulk Order Anti-Beta4-Spectrin Antibody

Product Specific References for Applications and Species

Immunocytochemistry: Mouse
PMID Dilution Publication
366046001:500Smalley, J.L., et al. 2023. Spectrin-beta 2 Facilitates the Selective Accumulation of GABAA Receptors at Somatodendritic Synapses. Communications Biology, 11.
354119841:500Wang, Y., et al. 2022. Glucose Increases the Length and Spacing of the Lattice Structure of the Axon Initial Segment. Microscopy Research and Technique, 2679-2691.
34534742not listedWang, Y., et al. 2021. The largest isoform of Ankyrin-G is required for lattice structure of the axon initial segment. Biochemical and biophysical research communications, 28-34.
32125730not listedJarjour, A.A., et al. 2020. The formation of paranodal spirals at the ends of CNS myelin sheaths requires the planar polarity protein Vangl2. Glia, 1840-1858.
29398366not listedJacko, M., et al. 2018. Rbfox Splicing Factors Promote Neuronal Maturation and Axon Initial Segment Assembly. Neuron, 853-868.
Immunohistochemistry: Mouse
PMID Dilution Publication
315911561:200Sozmen, E.G., et al. 2019. White matter stroke induces a unique oligo-astrocyte niche that inhibits recovery. Journal of Neuroscience, 39(47), pp.9343-9359.. Journal of Neuroscience, 9343-9359.
315329181:200Di Re, J., et al. 2019. Imaging of the Axon Initial Segment. Current Protocols in Neuroscience, e78.
Immunohistochemistry: Rat
PMID Dilution Publication
327363741:250Werginz, P., et al. 2020. The relationship between morphological properties and thresholds to extracellular electric stimulation in α RGCs. Journal of Neural Engineering, 45015.
325531161:250Hanemaaijer, N.A., et al. 2020. Ca 2+ entry through Na V channels generates submillisecond axonal Ca 2+ signaling. Elife, e54566.
Western Blot: Mouse
PMID Dilution Publication
366046001:1000Smalley, J.L., et al. 2023. Spectrin-beta 2 Facilitates the Selective Accumulation of GABAA Receptors at Somatodendritic Synapses. Communications Biology, 11.
31910261not listedLee, M., et al. 2020. Ecm29-mediated proteasomal distribution modulates excitatory GABA responses in the developing brain. Journal of Cell Biology, e201903033.
299565861:500Dash, B., et al. 2018. Nonmuscle myosin II isoforms interact with sodium channel alpha subunits. . Molecular pain, .
Western Blot: Rat
PMID Dilution Publication
287857241:1000Kneynsberg, A., et al. 2017. Aging Does Not Affect Axon Initial Segment Structure and Somatic Localization of Tau Protein in Hippocampal Neurons of Fischer 344 Rats. eNeuro, .

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