Anti-Bassoon Antibody (L124/59)

Name: Anti-Bassoon Antibody
Brand: NeuroMab
SKU: 75-491
Price: 295.0 USD
Availability: InStock

from NeuroMab Datasheet

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Clonality

Monoclonal

Applications

AT, ICC, IHC, WB

Host Species

Mouse

Gene Name

Bsn

Molecular Weight

400 kDa for full-length protein, many smaller bands possible depending on sample used

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Adult rat hippocampus immunohistochemistry.

Array tomography immunofluorescence of an LRWhite-embedded 70 nm section from adult mouse cortex with L124/59 (magenta), rabbit mAb PSD-95 (Cell Signaling #3450, green) and Hoechst nuclear stain (blue). The insert shows three consecutive sections through the synapse that is marked with a white box..

Product Details

Target

Protein bassoon

Target Description

Bassoon is a large (420-kDa) scaffolding protein specifically localized at the active zone of presynaptic nerve terminals. Bassoon is involved in the development of presynaptic terminals and in the regulation of neurotransmitter release at both excitatory and inhibitory brain synapses (Richter K. et al., 1999).

Format

Purified

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

L124/59

Isotype

IgG2b

Applications

AT, ICC, IHC, WB

Host Species

Mouse

Gene Name

Bsn

Molecular Weight

400 kDa for full-length protein, many smaller bands possible depending on sample used

Antigen

Fusion protein amino acids 157-517 (zinc finger domains) of rat Bassoon (also known as Zinc finger protein 231, BSN, ZNF231 and KIAA0434, accession number O88778); Mouse: 96% identity (349/363 amino acids identical); Human: 90% identity (325/361 amino acids identical); 40% identity with Piccolo

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_2744564

Storage

Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Buffer

10mM Tris, 50mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

Conjugate

Unconjugated

Quality Control

Each new lot of this antibody is tested to confirm that it shows the expected immunoperoxidase-diaminobenzidine / immunofluorescence staining pattern when used to stain brain sections.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from opening

Synonyms

Protein bassoon

UniProt Details

UniProt (Human): Q9UIX4
UniProt (Immunogen Species): A2BDX4

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Anti-Bassoon Antibody (L124/59)

Anti-Bassoon Antibody
SKU: 75-491

Product Details

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Anti-Bassoon Antibody (L124/59)

Anti-Bassoon Antibody SKU: 75-491

Product Details

Anti-Bassoon Antibody
SKU: 75-491