Anti-Ataxin-1, 11NQ Antibody (N76/8)

Name: Anti-Ataxin-1, 11NQ Antibody
Brand: NeuroMab
SKU: 75-117
Price: 308.0 USD
Availability: InStock

from NeuroMab Datasheet

Product Type

Primary Antibody

Species Reactivity

Human, Mouse, Rat

Clone

N76/8

Applications

IHC, IP, WB

Host Species

Mouse

Format

Purified

Gene Name

Atxn1 Sca1

Molecular Weight

85 kDa

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Transfected cell immunoblot: COS cells transiently transfected with Ataxin-1 and Kv2.1 plasmids and probed with N76/8 TC supe.

Adult rat brain immunoblot: extracts of cerebella from Ataxin-1 KO and WT mice and probed with N76/8 (left) or K89/41 (right) TC supe.

Adult rat cerebellum immunohistochemistry.

Adult rat hippocampus immunohistochemistry.

Transfected cell immunoblot: COS cells transiently transfected with Ataxin-1 and Kv2.1 plasmids and probed with N76/8 TC supe.

Volume: 100 µL

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Product Details

Target

Ataxin-1, 11NQ

Target Description

Ataxin1, also known as spinocerebellar ataxia type 1 protein homolog, is a highly conserved DNA-binding protein. Ataxin1 is expressed in brain and can be found at high levels in the cortex and the hypothalamus in neurons. It is also expressed in other tissues. Within the cell, it is highly expressed in the nucleus, and can also be found in the cytoplasm. Mutations in the ataxin-1 gene cause spinocerebellar ataxia type 1.

Format

Purified

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N76/8

Isotype

IgG2b

Applications

IHC, IP, WB

Host Species

Mouse

Gene Name

Atxn1 Sca1

Molecular Weight

85 kDa

Antigen

Synthetic peptide amino acids 164-197 (ATTPSQRSQLEAYSTLLANMGSLSQAPGHKVEPP) of mouse ataxin-1 (also known as spinocerebellar ataxia type 1 protein homolog accession number P54254); Rat: 100% identity (34/34 amino acids identical); Human: 88% identity (30/34 amino acids identical)

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_10673960

Storage

Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Buffer

10mM Tris, 50mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

Conjugate

Unconjugated

Specificity

No cross-reactivity reported

Quality Control

Each new lot of this antibody is tested to confirm that it shows the expected staining pattern when used to stain COS cells overexpressing target.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from opening

Synonyms

Ataxin-1 (Spinocerebellar ataxia type 1 protein homolog)

UniProt Details

UniProt (Human): P54254
UniProt (Immunogen Species): P54254

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Anti-Ataxin-1, 11NQ Antibody (N76/8)

Anti-Ataxin-1, 11NQ Antibody
SKU: 75-117

Bulk Order Anti-Ataxin-1, 11NQ Antibody

Product Details

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Anti-Ataxin-1, 11NQ Antibody (N76/8)

Anti-Ataxin-1, 11NQ Antibody SKU: 75-117

Bulk Order Anti-Ataxin-1, 11NQ Antibody

Product Details

Anti-Ataxin-1, 11NQ Antibody
SKU: 75-117