Acid sensing ion channel 1, Neuronal amiloride-sensitive cation channel 2 or ASIC1 is encoded by the gene ASIC1 and is a member of the Acid sensing ion channel (ASIC) family. ASIC1 acts as an acid sensing proton gated sodium channel and is thought to play a role in learning, pain transduction, memory development, and fear conditioning. ASIC1 is widely expressed in the central and peripheral nervous system. Diseases associated with ASIC1 include spatial learning and memory capability problems and Frozen Shoulder.
Purified by Protein A chromatography
Asic1 Accn2 Asic Bnac2
Fusion protein amino acids 460-526 (cytoplasmic C-terminus) of mouse ASIC1 (accession number Q6NXK8) produced recombinantly in E. Coli
Human, Mouse, Rat
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.
PBS with 0.09% azide
FL594 Ex: 594 nm, Em: 615 nm
Does not cross-react with ASIC2
Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
12 months from date of receipt
Shipped on ice packs
Acid-sensing ion channel 1 (ASIC1) (Acid-sensing ion channel) (Amiloride-sensitive cation channel 2, neuronal) (Brain sodium channel 2) (BNaC2)