Anti-Arx Antibody (N411/51)

Name: Anti-Arx Antibody
Brand: NeuroMab
SKU: 75-402
Price: 308.0 USD
Availability: InStock

from NeuroMab Datasheet

Product Type

Primary Antibody

Species Reactivity

Mouse, Rat

Clone

N411/51

Applications

ICC, IHC, WB

Host Species

Mouse

Format

Purified

Gene Name

Arx

Molecular Weight

70 kDa

Go to Full Product Details

"Immunofluorescence staining of wild-type (WT) and Parvalbumin-specific Arx knockout (ArxParvKO) mouse brains. Images courtesy of Eric Marsh (Children’s Hospital of Philadelphia)."

Adult rat reticular thalamic nucleus and zona incerta immunohistochemistry.

Adult/neonatal rat brain/cerebellum low-speed pellet (RBLSP/RCLSP) and transfected cell immunoblot: extracts of RBLSP, RCLSP and COS cells transiently transfected with Flag-tagged Arx or untagged Kv2.1 plasmid and probed with N411/51 (left) and N52A/42 (right) TC supe.

"Immunofluorescence staining of wild-type (WT) and Parvalbumin-specific Arx knockout (ArxParvKO) mouse brains. Images courtesy of Eric Marsh (Children’s Hospital of Philadelphia)."

Volume: 100 µL

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Product Details

Target

Homeobox protein ARX (Aristaless-related homeobox)

Target Description

Homeobox protein ARX, Aristaless-related homeobox or ARX is encoded by the gene ARX and is a member of the group-II aristaless-related protein family. ARX functions as a transcription factor and is thought to be involved in normal CNS development. ARX is expressed in brain and pancreas during development. Diseases associated with ARX include Early Infantile Epileptic Encephalopathy and X-linked Lissencephaly.

Format

Purified

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N411/51

Isotype

IgG1

Applications

ICC, IHC, WB

Host Species

Mouse

Gene Name

Arx

Molecular Weight

70 kDa

Antigen

Fusion protein amino acids 1-220 (N-terminus) of mouse Arx (also known as Homeobox protein ARX and Aristaless-related homeobox, accession number O35085); Rat: 97% identity (216/221 amino acids identical); Human: 92% identity (205/222 amino acids identical)

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_2491188

Storage

Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Buffer

10mM Tris, 50mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

Conjugate

Unconjugated

Quality Control

Each new lot of this antibody is tested to confirm that it shows the expected staining pattern when used to stain COS cells overexpressing target.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from opening

Synonyms

Homeobox protein ARX (Aristaless-related homeobox)

UniProt Details

UniProt (Human): Q96QS3
UniProt (Immunogen Species): O35085

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Anti-Arx Antibody (N411/51)

Anti-Arx Antibody
SKU: 75-402

Bulk Order Anti-Arx Antibody

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