Anti-Ankyrin-B Antibody (N105/17)
Our Anti-Ankyrin-B mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N105/17. It detects human, mouse, and rat Ankyrin-B, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.
![Immunoblot against crude membranes from whole mouse (MBM) or rat (RBM) brain and from human hippocampus [HBM(H)], cerebral cortex [HBM(Cx)] or cerebellum [HBM(Cb)] probed with N105/17 (left) or N52A/42 (right) TC supe.](http://www.antibodiesinc.com/cdn/shop/products/validation-image-73-145-n105-17-wb2_e458083f-a8e1-46d3-b693-7ab01cf099dd_{width}x.jpg?v=1626903511)
Immunoblot against crude membranes from whole mouse (MBM) or rat (RBM) brain and from human hippocampus [HBM(H)], cerebral cortex [HBM(Cx)] or cerebellum [HBM(Cb)] probed with N105/17 (left) or N52A/42 (right) TC supe.
![Immunoblot against crude membranes from whole mouse (MBM) or rat (RBM) brain and from human hippocampus [HBM(H)], cerebral cortex [HBM(Cx)] or cerebellum [HBM(Cb)] probed with N105/17 (left) or N52A/42 (right) TC supe.](http://www.antibodiesinc.com/cdn/shop/products/validation-image-73-145-n105-17-wb2_e458083f-a8e1-46d3-b693-7ab01cf099dd_1024x.jpg?v=1626903511)
Product Specific References for Applications and Species
- Immunocytochemistry: Mouse | Rat
- Immunohistochemistry: Guinea Pig | Mouse | Rat
- Immunoprecipitation: Rat
- STORM: Rat
- Western Blot: Mouse | Rat
| Immunocytochemistry: Mouse | ||
| PMID | Dilution | Publication |
| 33689679 | 1:10 | Chang, K.J., et al. 2021. TDP-43 maximizes nerve conduction velocity by repressing a cryptic exon for paranodal junction assembly in Schwann cells. . Elife, e64456. |
| 25362473 | not listed | Ho, T.S., et al. 2015. A hierarchy of ankyrin-spectrin complexes clusters sodium channels at nodes of Ranvier.. Nature Neuroscience, 1664-72. |
| Immunocytochemistry: Rat | ||
| PMID | Dilution | Publication |
| 31934859 | 1:500 | Yang, H.Q., et al. 2020. Ankyrin-G mediates targeting of both Na + and K ATP channels to the rat cardiac intercalated disc. Elife, e52373. |
| 22632975 | not listed | Galiano, M.R., et al. 2012. A distal axonal cytoskeleton forms an intra-axonal boundary that controls axon initial segment assembly.. Cell, 1125-1139. |
| 21518878 | not listed | Susuki, K., et al. 2011. Schwann cell spectrins modulate peripheral nerve myelination.. PNAS: USA, 8009-8014. |
| Immunohistochemistry: Guinea Pig | ||
| PMID | Dilution | Publication |
| 21390223 | 1:100 | Huff, T.B., et al. 2011. Real-time CARS imaging reveals a calpain-dependent pathway for paranodal myelin retraction during high-frequency stimulation.. PLoS One, e17176. |
| Immunohistochemistry: Mouse | ||
| PMID | Dilution | Publication |
| 36710500 | 1:300 | Cunningham, M.E., et al. 2023. Axolemmal Nanoruptures Arising from Paranodal Membrane Injury Induce Secondary Axon Degeneration in Murine Guillain-Barré Syndrome. Journal of the Peripheral Nervous System, 17-31. |
| 35671105 | 1:300 | McGonigal, R., et al. 2022. Schwann Cell Nodal Membrane Disruption Triggers Bystander Axonal Degeneration in a Guillain-Barré Syndrome Mouse Model. The Journal of Clinical Investigation, e158524. |
| 28128343 | not listed | Mooney, C.M., et al. 2017. RNA sequencing of synaptic and cytoplasmic Upf1-bound transcripts supports contribution of nonsense-mediated decay to epileptogenesis. Scientific Reports, 41517. |
| 25362471 | not listed | Chang, K.J., et al. 2014. Glial ankyrins facilitate paranodal axoglial junction assembly.. Nature Neuroscience, 1673-81. |
| 23728480 | not listed | Le Bras, B., et al. 2014. In vivo assembly of the axon initial segment in motor neurons.. Brian Structure and Function, 1433-1450. |
| 22131424 | not listed | Kaphzan, H., et al. 2011. Alterations in intrinsic membrane properties and the axon initial segment in a mouse model of Angelman syndrome.. Journal of Neuroscience, 17637-17648. |
| Immunohistochemistry: Rat | ||
| PMID | Dilution | Publication |
| 31934859 | 1:500 | Yang, H.Q., et al. 2020. Ankyrin-G mediates targeting of both Na + and K ATP channels to the rat cardiac intercalated disc. Elife, e52373. |
| 29853631 | not listed | Susuki, K., et al. 2018. Glial βII spectrin contributes to paranode formation and maintenance. Journal of Neuroscience, 6063-6075. |
| 21734302 | 1:2000 | Lysakowski, A., et al. 2011. Molecular microdomains in a sensory terminal, the vestibular calyx ending.. Journal of Neuroscience, 10101-10114. |
| Immunoprecipitation: Rat | ||
| PMID | Dilution | Publication |
| 25362471 | not listed | Chang, K.J., et al. 2014. Glial ankyrins facilitate paranodal axoglial junction assembly.. Nature Neuroscience, 1673-81. |
| STORM: Rat | ||
| PMID | Dilution | Publication |
| 31934859 | 1:50 | Yang, H.Q., et al. 2020. Ankyrin-G mediates targeting of both Na + and K ATP channels to the rat cardiac intercalated disc. Elife, e52373. |
| Western Blot: Mouse | ||
| PMID | Dilution | Publication |
| 31042147 | 1:100 | Wang, G., et al. 2019. Structural plasticity of actin-spectrin membrane skeleton and functional role of actin and spectrin in axon degeneration. Elife, e38730. |
| 24795561 | 1:1000 | Lugo, J.N., et al. 2014. Deletion of PTEN produces autism-like behavioral deficits and alterations in synaptic proteins.. Frontiers in Molecular Neuroscience, 27. |
| 24217619 | not listed | Zhang, C., et al. 2013. Membrane domain organization of myelinated axons requires βII spectrin.. The Journal of Biology, 437-443. |
| Western Blot: Rat | ||
| PMID | Dilution | Publication |
| 31934859 | 1:2000 | Yang, H.Q., et al. 2020. Ankyrin-G mediates targeting of both Na + and K ATP channels to the rat cardiac intercalated disc. Elife, e52373. |