Anti-ALB, Human Serum Albumin Recombinant Chicken Chimeric mAb FL550 Conjugate (3B8-H3-G1)

Name: Anti-ALB, Human Serum Albumin Recombinant Chicken Chimeric mAb FL550 Conjugate
Brand: Aves Labs
SKU: 78-600-FL550
Price: 562.0 USD
Availability: InStock

Our chicken Anti-ALB, Human Serum Albumin FL550 conjugate recombinant monoclonal antibody is a chimeric antibody derived from NeuroMab clone 3B8-H3-G1. It detects human ALB, Human Serum Albumin and is purified by affinity chromatography. Works in IHC, ICC.

Anti-ALB, Human Serum Albumin Recombinant Chicken Chimeric mAb FL550 Conjugate

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Applications

ICC, IHC

Host Species

Chicken

Conjugates and Formulations

Unconjugated

490

594

650

Biotin

Carrier-Free

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Data Sheet

SKU: 78-600-FL550

Volume: 200 µL

Variant

Price:

$562.00

Quantity:

Ships: 1-5 business days

Product Details

Target

ALB, Human Serum Albumin

Scientific Background

Human serum albumin (HSA) is the most abundant plasma protein, with a molecular weight of ~66 kDa, and plays a central role in maintaining osmotic pressure and transporting a wide range of endogenous and exogenous ligands. Structurally, HSA consists of three homologous domains, each further divided into subdomains, forming a highly flexible binding surface that accommodates fatty acids, hormones, metabolites, and therapeutic drugs. Its ligand-binding versatility contributes to critical functions in pH buffering, free radical scavenging, and drug pharmacokinetics. In addition to its transport and stabilizing roles, HSA serves as a clinical biomarker of liver function and nutritional status. Dysregulation of HSA levels is associated with pathological conditions such as liver disease, kidney dysfunction, sepsis, and cancer, underscoring its significance in both physiology and disease

Format

Purified by affinity chromatography

Concentration

Lot dependent: provided at 0.3-0.5 mg/mL

Clonality

Recombinant

Clone

3B8-H3-G1

Isotype

IgY

Applications

ICC, IHC

Host Species

Chicken

Gene Name

ALB

Molecular Weight

66 kDa

Excitation / Emission

FL550 Ex: 550 nm, Em: 575 nm

Immunogen

Human serum albumin

Immunogen Species

Human

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

This recombinant antibody is a chimeric antibody created by replacing the mouse heavy and light constant regions of clone 3B8-H3-G1 with chicken IgY heavy and light constant regions. As such this antibody retains the same binding performance as the original clone 3B8-H3-G1 but can be detected using standard anti-chicken secondary antibodies allowing flexibility for multiplexing applications. This antibody is expressed recombinantly in mammalian cells and then affinity purified from the cell culture media.

Buffer

1X PBS, 0.05% Sodium Azide pH 7.4

Dilution Ranges

ICC: 1:100

Conjugate

550

Specificity

No cross-reactivity reported

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

HSA; Albumin; PRO0903; PRO1341; serum albumin

UniProt ID

P02768
UniProt Summary: Binds water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs (Probable). Its main function is the regulation of the colloidal osmotic pressure of blood (Probable). Major zinc transporter in plasma, typically binds about 80% of all plasma zinc. Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma. Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner. The shared binding site between zinc and calcium at residue Asp-273 suggests a crosstalk between zinc and calcium transport in the blood. The rank order of affinity is zinc > calcium > magnesium. Binds to the bacterial siderophore enterobactin and inhibits enterobactin-mediated iron uptake of E.coli from ferric transferrin, and may thereby limit the utilization of iron and growth of enteric bacteria such as E.coli. Does not prevent iron uptake by the bacterial siderophore aerobactin.

NCBI Gene ID

213

Shipping

Shipped on ice packs

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Anti-ALB, Human Serum Albumin Recombinant Chicken Chimeric mAb FL550 Conjugate (3B8-H3-G1)

SKU: 78-600-FL550

Product Details

Bulk Order Anti-ALB, Human Serum Albumin Recombinant Chicken Chimeric mAb FL550 Conjugate

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