Our Anti-Adenylate Cyclase III primary antibody from PhosphoSolutions is rabbit polyclonal. It detects human, mouse, and rat Adenylate Cyclase III and is antigen affinity purified. It is great for use in WB, IHC, ICC.
Immunofluorescence of a section of rat hippocampus selectively labeling the neuronal cilia with anti-adenylate cyclase III (cat. 85-AC3, 1:10,000, red), labeling nuclei with anti-MECP2 (cat. 1205-MeCP2, 1:1000,green), and Hoechst staining of nuclear DNA.
Adenylate cyclase is the enzyme which produces the "second messenger" signaling molecule, cAMP from ATP. Type III adenylate cyclase is localized to the membranes surrounding neuronal cilia. Much is currently unknown about the function of primary cilia in vertebrates, however, recent work has begun to explore their role in neuronal signaling and neurogenesis (Fuchs and Schwark, 2004; Louvi and Grove 2011).
Antigen Affinity Purified
Polyclonal
IgG
ICC, IHC, WB
Rabbit
ADCY3
160, 200 kDa
Synthetic peptide corresponding to amino acid residues from the C-terminal region of rat adenylate cyclase III, conjugated to keyhole limpet hemocyanin (KLH).
Human, Mouse, Rat
AB_2492029
Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.
Specific for endogenous levels of the ~160 kDa adenylate cyclase III protein.
Western blots performed on each lot.
For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.
After date of receipt, stable for at least 1 year at -20°C.
Blue Ice
AC-III antibody, AC3 antibody, ADCY3 antibody, ADCY3_HUMAN antibody, adenylate cyclase 3 antibody, Adenylate cyclase antibody, Adenylate cyclase type 3 antibody, Adenylate cyclase type III antibody, Adenylyl cyclase 3 antibody, ATP pyrophosphate lyase antibody, ATP pyrophosphate-lyase 3 antibody, olfactive type antibody
