Anti-ACT Antibody

Name: Anti-ACT Antibody
Brand: PhosphoSolutions
SKU: 24150
Price: 456.0 USD
Availability: InStock

Our ACT rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It detects human ACT and is antigen affinity purified. It is great for use in WB.

Western Blot of testis lysate showing specific immunolabeling of FHL5.

Click on image to zoom

Species Reactivity

Human

Applications

ELISA, WB

Host Species

Rabbit

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Data Sheet

SKU: 24150

Title: 100 µL

Variant

Price:

$456.00

Quantity:

Ships: 1-2 business days

Product Details

Target

ACT

Scientific Background

Transcriptional activation of CREB and CREM are required for proper cellular differentiation. A novel protein, activator of CREM in testis (ACT), is expressed with CREM.

Format

Antigen Affinity Purified

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB

Host Species

Rabbit

Gene Name

TRAF3IP2

Immunogen

Synthetic peptide corresponding to amino acids from the N-terminal region of human ACT protein

Immunogen Species

Human

Species Reactivity

Human

Storage

Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.

Physical State

Liquid

Buffer

PBS + 0.02% NaN3

Dilution Ranges

WB: 1:500-1:1000
WB Brain: 1:500-1:1000

Specificity

Reacts with the N-terminal region of human ACT protein

Quality Control

Western blots performed on each lot.

Usage Statement

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Country of Origin

United States

Expiration

After date of receipt, stable for at least 1 year at -20°C.

Synonyms

ACT1; TRAF3IP2; C6orf4; C6orf5; C6orf6; CANDF8; CIKS; PSORS13; adapter protein CIKS; NFkB-activating protein ACT1; connection to IKK and SAPK/JNK; nuclear factor NF-kappa-B activator 1; activator of CREM in testis; Activator of cAMP-responsive element modulator in testis; FLH5

UniProt ID

O43734
UniProt Summary: E3 ubiquitin ligase that catalyzes 'Lys-63'-linked polyubiquitination of target protein, enhancing protein-protein interaction and cell signaling. Transfers ubiquitin from E2 ubiquitin-conjugating enzyme UBE2V1-UBE2N to substrate protein. Essential adapter molecule in IL17A-mediated signaling. Upon IL17A stimulation, interacts with IL17RA and IL17RC receptor chains through SEFIR domains and catalyzes 'Lys-63'-linked polyubiquitination of TRAF6, leading to TRAF6-mediated activation of NF-kappa-B and MAPkinase pathways.

NCBI Gene ID

10758

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Anti-ACT Antibody

SKU: 24150

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