Serial dilutions of BSA-conjugated modified and unmodified nucleotides dotted onto membrane and probed with N297/59 TC supe (left) and a rabbit polyclonal control (right).
5-hydroxymethylcytidine is a DNA pyrimidine nitrogen base derived from cytosine. It is potentially important in epigenetics. In mammals and is thought to be important in gene regulation. 5-hydroxymethylcytidine can be generated by oxidation of 5-methylcytosine, a reaction mediated by the Tet family of enzymes. 5-hydroxymethylcytidine is found in many tissue types.
Synthetic nucleotide of 5-hydroxymethylcytidine. This NeuroMab antibody is considered "Restricted" and is therefore not available for commercial re-distribution on a for-profit basis.
Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Reacts preferentially with 5-hydroxymethylcytidine than with 5-methylcytidine
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
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