Alpha synuclein control peptide (116-131), Human, Purified Peptide

Name: Alpha synuclein control peptide (116-131), Human, Purified Peptide
Brand: Biosensis
SKU: PE-1606-100
Price: 97.0 USD
Availability: InStock

Alpha synuclein control peptide (116-131), purified human peptide, suitable to block.

Applications

Block

Host Species

Synthetic

Go to Full Product Details

Data Sheet

SKU: PE-1606-100

Volume/Size: 100 µg

Variant

Price:

$97.00

Quantity:

Ships: 1-2 business days

Product Details

Target

Alpha-synuclein

Scientific Background

Alpha synuclein is an abundant 140 amino acid neuronal protein, expressed primarily at presynaptic terminals in the central nervous system. Alpha synuclein has been associated with several neurodegenerative diseases. A point mutation in the gene coding for the alpha-synuclein protein was the first discovery linking this protein to a rare familial form of Parkinson's disease (PD). Subsequently, other mutations in the alpha-synuclein gene have been identified in familial PD. The aggregated proteinaceous inclusions called Lewy bodies found in PD and cortical Lewy body dementia (LBD) were discovered to be predominantly alpha-synuclein. Aberrant aggregation of alpha-synuclein has been detected in an increasing number of neurodegenerative diseases, collectively known as synucleopathies. Alpha-synuclein exists physiologically in both soluble and membrane-bound states, in unstructured and alpha-helical conformations, respectively. The physiological function of alpha-synuclein appears to require its translocation between these subcellular compartments and interconversion between the 2 conformations. Abnormal processing of alpha-synuclein is predicted to lead to pathological changes in its binding properties and function.

Format

Purified

Applications

Block

Host Species

Synthetic

Storage

This peptide is soluble in PBS and water. After reconstitution keep at -20°C. Avoid repetitive freeze/thaw cycles.

Physical State

Lyophilized

Production Notes

> 90% purity

Application Details

Control Peptide. This peptide may be used to block the binding activity of antibodies to alpha synuclein (see antibodies catalog # S-024-100 and S-075-50).

Usage Statement

For research use only.

Country of Origin

United States

Expiration

12 months after date of receipt (unopened vial).

Synonyms

Non-A beta component of AD amyloid; Non-A4 component of amyloid precursor; NACP

UniProt ID

P37840

Shipping

25°C (ambient)

Recover password

Create my account

Alpha synuclein control peptide (116-131), Human, Purified Peptide

SKU: PE-1606-100

Product Details

Bulk Order Alpha synuclein control peptide (116-131), Human, Purified Peptide

Related Products

Recently Viewed