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Products: Primary Antibodies

Anti-AGPS neo-epitope Antibody (N444/63)

NeuroMab Logo from NeuroMab

 Datasheet

PRODUCT OPTIONS

Brand Catalog # Option Volume Concentration Price
Brand
NeuroMab Logo
Catalog #
75-434
Option
Purified
Volume
100 µL
Concentration
1 mg/mL
Price
$275.00
Brand
NeuroMab Logo
Catalog #
73-434
Option
TC Supernatant
Volume
5 mL
Concentration
Lot dependent
Price
$275.00

Validation Images


Product Details

Antibody Type:

Monoclonal

Host Species:

Mouse

Antibody Isotype:

IgG1

Species Reactivity:

Human Mouse Rat

Applications:
WB Western Blot
IHC Immunohistochemistry
ICC Immunocytochemistry
IP Immunoprecipitation
AT Array Tomography
EM Electron Microscopy
CHIP Chromatin Immunoprecipitation
DB Dot Blot

ICC IHC WB

Target Description:

Alkyldihydroxyacetonephosphate synthase, peroxisomal or AGPS neo-epitope is encoded by the gene AGPS. AGPS is a member of the FAD-binding oxidoreductase/transferase type 4 family and is an enzyme involved in ether lipid biosynthesis. Diseases associated with this gene include forms of Rhizomelic Chondrodysplasia Punctata.

Immunogen:

Synthetic peptide amino acids 59-67 (KARRAASAA, site of proteolytic processing for peroxisome import) of human AGPS (also known as Alkylglycerone-phosphate synthase, Peroxisomal alkyldihydroxyacetonephosphate synthase, Alkyl-DHAP synthase, Aging-associated gene 5 protein, Ads and AAG5, accession number O00116)
Mouse: 100% identity (9/9 amino acids identical)
Rat: 100% identity (9/9 amino acids identical)

Cross Reactivity:

Does not cross-react with unprocessed AGPS

Protein Name(s):

Alkyldihydroxyacetonephosphate synthase, peroxisomal (Alkyl-DHAP synthase) (EC 2.5.1.26) (Aging-associated gene 5 protein) (Alkylglycerone-phosphate synthase)

Gene Name(s):

AGPS AAG5

Antibody Registry ID:

Purified: AB_2629423
TC Supernatant: AB_2532090


Antibody Validation and Application Notes


This antibody has been validated using the following assays:
Western Blot:

This antibody recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.

Immunohistochemistry:
This antibody shows the expected immunoperoxidase-diaminobenzidine / immunofluorescence staining pattern when used to stain brain sections.

Molecular Weight:

66 kDa processed (vs. 72 kDa unprocessed)


Quality Control


The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.

Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.