Pharmacology: A specific inhibitor of importin alpha/beta-mediated nuclear import with no effect on a range of other nuclear import pathways (1). Displays potent antiviral activity against HIV-1, dengue (1), corona (2) and other viruses. Clinically useful broad-spectrum antiparasitic agent (3). PubChem CID: 6321424.
Product is sold for research use only. Not for human therapeutic use or for medicinal purposes.
Purified
Neutralize
Soluble in DMSO. May be dissolved in DMSO up to 40 mg/mL. Store desiccated as supplied at -20°C for up to 2 years. Store solutions at -20°C for up to 1 month. Prevent multiple freeze-thaw cycles.
Dry, white powder
>98% purity (TLC); NMR (Conforms) Contains up to 10% B1b form.
Positive allosteric modulator of the alpha-7 neuronal nicotinic acetylcholine receptor and the purinergic P2X4 receptor. Antihelmintic. Also modulates glutamate- and GABA-activated chloride channels. Potentiates glycine-gated currents at low concentrations (30 nM).
For research use only.
United States
Store desiccated as supplied at -20°C for up to 2 years. Store solutions at -20°C for up to 1 month. Prevent multiple freeze-thaw cycles.
Ivermectin B1a; Dihydroavermectin B1a; CAS 70288-86-7
25°C (ambient)
Bulk Order Ivermectin, Purified Small Molecule (Species Independent)
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