Anti-GluA1/GluR1 Glutamate Receptor Recombinant Chicken Chimeric mAb FL594 Conjugate (N355/1)

Name: Anti-GluA1/GluR1 Glutamate Receptor Recombinant Chicken Chimeric mAb FL594 Conjugate
Brand: Aves Labs
SKU: 78-327-FL594
Price: 562.0 USD
Availability: InStock

Our chicken Anti-GluA1/GluR1 glutamate receptor FL594 conjugate recombinant monoclonal antibody is a chimeric antibody derived from NeuroMab clone N355/1. It detects human, mouse, and rat GluA1/GluR1 is purified by affinity chromatography. It works in IHC, ICC.

Anti-GluA1/GluR1 Glutamate Receptor Recombinant Chicken Chimeric mAb FL594 Conjugate

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Species Reactivity

Human, Mouse, Rabbit, Rat

Applications

ICC, IHC

Host Species

Chicken

Conjugates and Formulations

Unconjugated

490

550

650

Carrier-Free

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Data Sheet

Trial Size

SKU: 78-327-FL594

Volume: 200 µL

Variant

Price:

$562.00

Quantity:

Ships: 1-2 business days

Product Details

Target

GluA1/GluR1 glutamate receptor

Scientific Background

Glutamate receptor 1 or GluA1/GluR1 glutamate receptor is a member of the glutamate-gated ion channel family. GluR1 funcitons as an excitatory neurotransmitter at many synapses in the central nervous system and is widely expressed in brain. Mutations in the GluR1 gene are associated with cerebral cortical dysplasia, Status Epilepticus, and depression.

Format

Purified by affinity chromatography

Concentration

0.5 mg/mL

Clonality

Recombinant

Clone

N355/1

Isotype

IgY

Applications

ICC, IHC

Host Species

Chicken

Gene Name

Gria1 Glur1

Molecular Weight

100 kDa

Excitation / Emission

FL594 Ex: 594 nm, Em: 615 nm

Immunogen

Fusion protein amino acids 1-389 (extracellular N-terminus) of rat GluA1/GluR1 (accession number P19490) produced recombinantly in E. Coli.

Immunogen Species

Rat

Species Reactivity

Human, Mouse, Rabbit, Rat

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

This recombinant antibody is a chimeric antibody created by replacing the mouse heavy and light constant regions of clone N355/1 with chicken IgY heavy and light constant regions. As such this antibody retains the same binding performance as the original clone N355/1 but can be detected using standard anti-chicken secondary antibodies allowing flexibility for multiplexing applications. This antibody is expressed recombinantly in mammalian cells and then affinity purified from the cell culture media and conjugated.

Buffer

1X PBS, 0.05% Sodium Azide pH 7.4

Dilution Ranges

IHC: 1:250-1:1000
ICC: 1:250-1:1000

Conjugate

594

Specificity

Does not cross-react with GluR2

Quality Control

Each new lot of antibody is quality control tested by Western blot on rat brain membrane fraction and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Synonyms

Glutamate receptor 1 (GluR-1) (AMPA-selective glutamate receptor 1) (GluR-A) (GluR-K1) (Glutamate receptor ionotropic, AMPA 1) (GluA1)

UniProt ID

P19490

Shipping

Shipped on ice packs

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Anti-GluA1/GluR1 Glutamate Receptor Recombinant Chicken Chimeric mAb FL594 Conjugate (N355/1)

SKU: 78-327-FL594

Product Details

Bulk Order Anti-GluA1/GluR1 Glutamate Receptor Recombinant Chicken Chimeric mAb FL594 Conjugate

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