Anti-Vitronectin Antibody (HV2)
Our human Vitronectin monoclonal antibody from Antibodies Incorporated is produced in-house from clone HV2. It detects human Vitronectin and is Protein A or Protein G purified. Works in AP, ELISA, IHC, WB.
Immunohistochemistry detection of Vitronectin in human cancerous liver tissue using Anti-Vitronectin Antibody (Cat. CSI 003-02-010). Tissue was mounted and pariffin fixed. Heat induced antigen retrieval was performed using citrate buffer, heated, and then blocked. After washing, the primary antibody (Cat. CSI 003-02-010) was incubated with the sample.
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SKU: CSI 003-02-010
Ships: 1-2 business days
Product Details
Vitronectin
Vitronectin is a plasma glycoprotein that circulates in the blood. Vitronectin is circulating as a mixture of both 75 kDa and 65 kDa forms. Vitronectin is a major cell adhesive glycoprotein and is a common component of extracellular matrix and plasma. It competes effectively with other plasma proteins and is often involved in cell attachment, regulation of blood coagulation and immune responses. It has similar tissue distribution to fibronectin and also its integrin receptor recognizes fibronectin. (2)
Protein A or Protein G purified
1 mg/mL ±15%
Monoclonal
HV2
IgG2b/k
ELISA, IHC, WB
Human
VTN
65 kDa, 75 kDA
Human vitronectin purified from plasma by heparin-affinity chromatography
Human
Human
2-8°C without exposure to light
Liquid
BSA free
0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide
CSI 003-02 binds to vitronectin in ELISA when vitronectin is coated directly onto the microtiter well. In Western blotting a dilution guideline of 1/100 has proved successful. (1,2) AP: CSI 003-02 can be used to purify vitronectin from human plasma by affinity chromatography. It can also be used to quantitatively affinity-deplete human plasma or serum of vitronectin. It partially denatures vitronectin upon antibody binding.
Unconjugated
Vitronectin (human). The epitope is located in the connecting region. Binding can be competed selectively by a peptide comprising aa 121-133.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
United States
24 months from date of receipt
VTN, V75, VN, VNT, vitronectin, complement S-protein, epibolin, serum spreading factor, somatomedin B
7448
Shipped on ice packs

