Anti-TrpV3 Antibody (N15/4)

Name: Anti-TrpV3 Antibody
Brand: NeuroMab
SKU: 75-043
Price: 337.0 USD
Availability: InStock

Our mouse TrpV3 monoclonal antibody from NeuroMab is produced in-house from clone N15/4. It detects human, mouse, and rat TrpV3 and is purified by Protein A chromatography. Works in WB, ICC, IP, ELISA.

Transfected HEK293 cell immunofluorescence staining N15/4 TC supe =green, DAPI=blue.

Transfected cell immunoblot. Extracts of COS-1 cells transiently transfected with rat TrpV3 (left lane) or rat Kv2.1 (right lane) plasmids and probed with K89/34 TC supe (left panel) or pure N15/4 (right panel).

Transfected HEK293 cell immunofluorescence staining N15/4 TC supe =green, DAPI=blue.

Click on image to zoom

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, ICC, IP, WB

Host Species

Mouse

Conjugates and Formulations

490

550

594

650

Biotin

Carrier-Free

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Data Sheet

SKU: 75-043

Volume: 100 µL

Variant

Price:

$337.00

Quantity:

Ships: 1-2 business days

Product Details

Target

TrpV3

Scientific Background

Transient receptor potential cation channel subfamily V member 3 or TrpV3 is encoded by the gene TprV3. TrpV3 is a member of the transient receptor potential cation channel family. TrpV3 is thought to function in a variety of processes, including temperature sensation and vasoregulation. This channel is activated at temperatures between 22 and 40 °C. TrpV3 is found at the membrane in the CNS, PNS and skin where it acts as a transducer of thermal stimuli. Diseases associated with TRPV3 include several types of Keratoderma.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N15/4

Isotype

IgG2a

Applications

ELISA, ICC, IP, WB

Host Species

Mouse

Gene Name

TrpV3

Molecular Weight

70 kDa

Immunogen

Synthetic peptide amino acids 774-791 (cytoplasmic C-terminus) of rat TrpV3 (KTTLYAFDELDEFPETSV; accession number E9PU00)

Immunogen Species

Rat

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_10671952

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.4

Dilution Ranges

WB: 1:1000
ICC: 1:100

Conjugate

Unconjugated

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Synonyms

Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3)

UniProt ID

E9PU00

Shipping

Shipped on ice packs

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Anti-TrpV3 Antibody (N15/4)

SKU: 75-043

Product Details

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