Anti-Testicular Receptor 2 (TR2) Antibody

Name: Anti-Testicular Receptor 2 (TR2) Antibody
Brand: PhosphoSolutions
SKU: 2002-TR2
Price: 394.0 USD
Availability: InStock

Our Anti-Testicular Receptor 2 (TR2) primary antibody from PhosphoSolutions is rabbit polyclonal. It detects human, mouse, and rat Testicular Receptor 2 (TR2) and is neat serum. It is great for use in WB.

Western blot of rat testicular lysate showing specific immunolabeling of the ~64 kDa TR2 protein.

Click on image to zoom

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, WB

Host Species

Rabbit

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Data Sheet

Trial Size

SKU: 2002-TR2

Volume: 100 µL

Variant

Price:

$394.00

Quantity:

Ships: 1-2 business days

Product Details

Target

Testicular Receptor 2 (TR2)

Scientific Background

Testicular receptor 2 (TR2) is a member of the orphan nuclear receptor family. It is widely expressed at a low level throughout the adult testis. TR2 represses transcription and binds DNA directly interacting with HDAC3 and HDAC4 via DNA-binding domains (Franco et al., 2003). TR2 has also been implicated in regulation of estrogen receptor activity in mammary glands (Hun et al., 2002). In addition, TR2 has recently been shown to form a heterodimer with TR4 that can bind to the direct repeat 6 element of the hepatitis B virus (HBV) enhancer II region thus suppressing HBV gene expression (Lin et al., 2008).

Format

Neat Serum

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB

Host Species

Rabbit

Gene Name

NR2C1

Molecular Weight

64 kDa

Immunogen

Fusion protein from the N-terminal region of mouse TR2.

Immunogen Species

Mouse

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2492264

Storage

Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.

Physical State

Liquid

Production Notes

Neat Serum

Buffer

Neat serum

Dilution Ranges

WB: 1:1000

Conjugate

Unconjugated

Specificity

Specific for endogenous levels of the ~64 kDa TR2 protein.

Quality Control

Western blots performed on each lot.

Usage Statement

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Expiration

After date of receipt, stable for at least 1 year at -20°C.

Synonyms

NR2C 1 antibody, NR2C1 antibody, NR2C1_HUMAN antibody, NUCLEAR HORMONE RECEPTOR TR2 antibody, Nuclear receptor subfamily 2 Group C isoform antibody, Nuclear receptor subfamily 2 group C member 1 antibody, Orphan nuclear receptor TR2 antibody, Testicular receptor 2 antibody, TR 2 antibody, TR2 antibody, TR2-11 antibody

UniProt ID

Q505F1

NCBI Gene ID

22025

Shipping

Blue Ice

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Anti-Testicular Receptor 2 (TR2) Antibody

SKU: 2002-TR2

Product Details

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