Anti-TARPGamma2/Stargazin Antibody (N245/1)

Name: Anti-TARPGamma2/Stargazin Antibody
Brand: NeuroMab
SKU: 75-242
Price: 337.0 USD
Availability: InStock

Our mouse TARPGamma2/Stargazin monoclonal antibody from NeuroMab is produced in-house from clone N245/1. It detects mouse and rat TARPGamma2/Stargazin and is purified by Protein A chromatography. Works in WB, ICC, ELISA.

Immunoblot versus low-speed pellet samples from wild-type (WT) and Stargazer mutant (STG) mice and probed with N245/1 TC supe. Data courtesy of Susumu Tomita, Yale University.

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Species Reactivity

Mouse, Rat

Applications

ELISA, ICC, WB

Host Species

Mouse

Conjugates and Formulations

490

550

594

650

Biotin

Carrier-Free

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Data Sheet

KO Validated

SKU: 75-242

Volume: 100 µL

Variant

Price:

$337.00

Quantity:

Ships: 1-2 business days

Product Details

Target

TARPGamma2/Stargazin

Scientific Background

Voltage-dependent calcium channel gamma-2 subunit, TARPGamma2 or Stargazin is encoded by the gene CACNG2 and is the transmembrane gamma subunit of the L-type calcium channel. Stargazin is in involved in regulation and trafficking of the ligand gated ion channel AMPA receptors. It is thought to play a role in learning and memory. Diseases associated with this gene include forms of deafness, Mental Retardation and childhood absnce epilepsy.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N245/1

Isotype

IgG2a

Applications

ELISA, ICC, WB

Host Species

Mouse

Gene Name

Cacng2 Stg

Molecular Weight

36 kDa

Immunogen

Fusion protein amino acids 203-323 (cytoplasmic C-terminus) of rat TARPGamma2 (accession number Q71RJ2) produced recombinantly in E. Coli

Immunogen Species

Rat

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_11001587

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Conjugate

Unconjugated

Specificity

Does not cross-react with TARPGamma3, TARPGamma4 and TARPGamma8

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Synonyms

Voltage-dependent calcium channel gamma-2 subunit (Neuronal voltage-gated calcium channel gamma-2 subunit) (Stargazin) (Transmembrane AMPAR regulatory protein gamma-2) (TARP gamma-2)

UniProt ID

Q71RJ2

Shipping

Shipped on ice packs

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Anti-TARPGamma2/Stargazin Antibody (N245/1)

SKU: 75-242

Product Details

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