Anti-SynCAM1 Antibody (L45/30)

Name: Anti-SynCAM1 Antibody
Brand: NeuroMab
SKU: 75-120
Price: 337.0 USD
Availability: InStock

Our mouse SynCAM1 monoclonal antibody from NeuroMab is produced in-house from clone L45/30. It detects human, mouse, and rat SynCAM1 and is purified by Protein A chromatography. Works in WB, ICC, ELISA.

Adult whole rat brain homogenate immunoblot.

Transfected cell immunoblot: extracts of COS-7 cells transiently transfected with SynCAM1, SynCAM2 or SynCAM3 plasmids and probed with L45/30 TC supe. Image courtesy of Dr. Philip Washbourne, Institute of Neuroscience, University of Oregon.

Adult whole rat brain homogenate immunoblot.

Click on image to zoom

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, ICC, WB

Host Species

Mouse

Conjugates and Formulations

490

550

594

650

Biotin

Carrier-Free

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Data Sheet

SKU: 75-120

Volume: 100 µL

Variant

Price:

$337.00

Quantity:

Ships: 1-2 business days

Product Details

Target

SynCAM1

Scientific Background

SynCAM1 cell adhesion molecule, Immunoglobulin superfamily member 4 (IgSF4), or Nectin-like protein 2 (NECL-2) is encoded by the gene CADM1 and is a member of the Immunoglobulin-like Cell Adhesion Molecules family. SynCam1 is a cell adhesion molecule involved in many cell processes including the mediation of cell-cell adhesion and assembly, neuronal migration axon growth and differentiation. SynCAM1 is expressed in many tissue types including, brain, lung, kidney, heart, spleen and liver. Diseases associated with this gene include Retroperitoneal Fibrosis and Neuromyelitis Optica Spectrum Disorder.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

L45/30

Isotype

IgG1

Applications

ELISA, ICC, WB

Host Species

Mouse

Gene Name

Cadm1 Igsf4 Necl2 Ra175 Syncam SynCam1 Tslc1

Molecular Weight

50 kDa

Immunogen

Fusion protein amino acids 257-388 of mouse SynCAM1 (accession number Q8R5M8), recognizes 1.4b isoform only (epitope narrowed to GLTQLPNSAEELDSEDLS) produced recombinantly in E. Coli

Immunogen Species

Mouse

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2068036

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.47

Conjugate

Unconjugated

Specificity

No cross-reactivity with SynCAM2 or SynCAM3

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Synonyms

Cell adhesion molecule 1 (Immunoglobulin superfamily member 4) (IgSF4) (Nectin-like protein 2) (NECL-2) (Spermatogenic immunoglobulin superfamily) (SgIgSF) (Synaptic cell adhesion molecule) (SynCAM) (Tumor suppressor in lung cancer 1) (TSLC-1)

UniProt ID

Q8R5M8

Shipping

Shipped on ice packs

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Anti-SynCAM1 Antibody (L45/30)

SKU: 75-120

Product Details

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