Anti-SUR1 and SUR2B Antibody (N323A/31)

Name: Anti-SUR1 and SUR2B Antibody
Brand: NeuroMab
SKU: 75-298
Price: 337.0 USD
Availability: InStock

Our mouse SUR1 and SUR2B monoclonal antibody from NeuroMab is produced in-house from clone N323A/31. It detects mouse and rat SUR1 and SUR2B and is purified by Protein A chromatography. Works in WB, ICC, ELISA.

Immunoblot versus extracts of heart tissue from WT and SUR2 KO mice probed with N323A/31 TC supe. Data courtesy of William Coetzee and Margaret Rice, New York University SOM.

Click on image to zoom

Species Reactivity

Mouse, Rat

Applications

ELISA, ICC, WB

Host Species

Mouse

Conjugates and Formulations

490

550

594

650

Biotin

Carrier-Free

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Data Sheet

SKU: 75-298

Volume: 100 µL

Variant

Price:

$337.00

Quantity:

Ships: 1-2 business days

Product Details

Target

SUR1 and SUR2B

Scientific Background

SUR1 and SUR2B are members of the ATP binding cassette transporter subfamily C. These proteins combine with KCNJ8(Kir6.1) or KCNJ11(Kir6.2) to form K+ATP channels and are involved in their regulation and activation.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N323A/31

Isotype

IgG1

Applications

ELISA, ICC, WB

Host Species

Mouse

Gene Name

Abcc8 Sur Sur1 Abcc9 Sur2

Molecular Weight

175 kDa (and smaller fragments likely due to proteolytic cleavage)

Immunogen

Fusion protein amino acids 1503-1545 (VHTILTADLVIVMKRGNILEYDTPESLLAQEDGVFASFVRADM, cytoplasmic C-terminus) of rat SUR2B (accession number Q63563-2) produced recombinantly in E. Coli

Immunogen Species

Rat

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_2315926

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Conjugate

Unconjugated

Specificity

Cross-reacts with SUR1

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Synonyms

ATP-binding cassette sub-family C member 8 (Sulfonylurea receptor 1) ATP-binding cassette sub-family C member 9 (Sulfonylurea receptor 2)

UniProt ID

Q63563-2

Shipping

Shipped on ice packs

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Anti-SUR1 and SUR2B Antibody (N323A/31)

SKU: 75-298

Product Details

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