Anti-NKCC1 Antibody (N161/20)
Our Anti-NKCC1 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N161/20. It detects human, mouse, and rat NKCC1, and is purified by Protein A chromatography. It is great for use in DB.
SKU: 75-229
Product Details
NKCC1
NKCC1 or Solute carrier family 12 member 2, is encoded by the gene SLC12A2. NKCC1 is a membrane bound protein that is involved in sodium, potassium and chloride transport and reabsorption and is expressed in many tissues.
Purified by Protein A chromatography
1 mg/mL
Monoclonal
N161/20
IgG1
Mouse
SLC12A2 NKCC1
131 kDa
Synthetic peptide amino acids 208-223 (YYLR[pT]FGHN[pT]MDAVPR) of human NKCC1 (accession number P55011)
Human, Mouse, Rat
AB_2285991
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Liquid
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125
Unconjugated
Cross-reacts with non-phosphorylated protein by ELISA
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
United States
24 months from date of receipt
Shipped on ice packs
Solute carrier family 12 member 2 (Basolateral Na-K-Cl symporter) (Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 1)
UniProt (Human): P55011
UniProt (Immunogen Species): P55011
UniProt (Immunogen Species): P55011
- Campbell SL, Robel S, Cuddapah VA, Robert S, Buckingham SC, Kahle KT, Sontheimer H. (2015), 'GABAergic disinhibition and impaired KCC2 cotransporter activity underlie tumor-associated epilepsy..' Glia. 10.1002/glia.22730.
- Antoine MW, Hübner CA, Arezzo JC, Hébert JM. (2013), 'A causative link between inner ear defects and long-term striatal dysfunction..' Science. 10.1126/science.1240405.