Anti-GIT2 Antibody (N83/48)

Name: Anti-GIT2 Antibody
Brand: NeuroMab
SKU: 75-126
Price: 337.0 USD
Availability: InStock

Our mouse GIT2 monoclonal antibody from NeuroMab is produced in-house from clone N83/48. It detects human, mouse, and rat GIT2 and is purified by Protein A chromatography. Works in WB, IHC, IP, ELISA.

Adult rat hippocampus immunohistochemistry.

Transfected cell immunoblot: extracts of rat brain membranes (RBM) and COS cells transiently transfected with Flag-tagged GIT1 and GIT2 and untagged Kv2.1 plasmids and probed with N83/48 (left) and K89/41 (right) TC supe and with anti-Flag antibody (middle).

Adult rat hippocampus immunohistochemistry.

Click on image to zoom

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, IHC, IP, WB

Host Species

Mouse

Conjugates and Formulations

490

550

594

650

Biotin

Carrier-Free

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Data Sheet

SKU: 75-126

Volume: 100 µL

Variant

Price:

$337.00

Quantity:

Ships: 1-2 business days

Product Details

Target

GIT2

Scientific Background

G-protein coupled receptor kinase interacting ArfGAP 2 is encoded by the gene GIT2. GIT2 is a member of the GIT protein family. GIT2 has a be shown to repress lamellipodial extension and focal adhesion turnover, and is thought to regulate cell motility. GIT2 is expressed in 207 organs with the highest expression level in the right hemisphere of cerebellum. Diseases associated with GIT2 include Gastric Antral Vascular Ectasia and Systemic Scleroderma.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N83/48

Isotype

IgG1

Applications

ELISA, IHC, IP, WB

Host Species

Mouse

Gene Name

GIT2 KIAA0148

Molecular Weight

85 kDa

Immunogen

Fusion protein amino acids 450-759 (C-terminus) of human GIT2 (accession number Q14161) produced recombinantly in E. Coli

Immunogen Species

Human

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2110013

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.53

Conjugate

Unconjugated

Specificity

No cross-reactivity against GIT1

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Synonyms

ARF GTPase-activating protein GIT2 (ARF GAP GIT2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT-2) (CAT2) (G protein-coupled receptor kinase-interactor 2) (GRK-interacting protein 2)

UniProt ID

Q14161

Shipping

Shipped on ice packs

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Anti-GIT2 Antibody (N83/48)

SKU: 75-126

Product Details

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