Anti-Fig4/Sac3 Antibody (N202/7)

Name: Anti-Fig4/Sac3 Antibody
Brand: NeuroMab
SKU: 75-201
Price: 337.0 USD
Availability: InStock

Our mouse Fig4/Sac3 monoclonal antibody from NeuroMab is produced in-house from clone N202/7. It detects human, mouse, and rat Fig4/Sac3 and is purified by Protein A chromatography. Works in WB, IHC, ICC, ELISA.

$Immunoblot against crude membrane fractions from whole mouse (MBM) or rat (RBM) brain and from human hippocampus [HBM(H)], cerebral cortex [HBM(Cx)] or cerebellum [HBM(Cb)] and probed with N202/7 (left) or N52A/42 (right) TC supe.$

Immunoblot against adult rat brain membranes (RBM) and samples from wild-type (WT) and Fig4/Sac3 knockout (KO) mice probed with N202/7 (left) and K89/41 (right) TC supe. Mouse brain samples courtesy of Miriam Meisler (University of Michigan).

Immunoblot against crude membrane fractions from whole mouse (MBM) or rat (RBM) brain and from human hippocampus [HBM(H)], cerebral cortex [HBM(Cx)] or cerebellum [HBM(Cb)] and probed with N202/7 (left) or N52A/42 (right) TC supe.

Click on image to zoom

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, ICC, IHC, WB

Host Species

Mouse

Conjugates and Formulations

490

550

594

650

Biotin

Carrier-Free

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Data Sheet

KO Validated

SKU: 75-201

Volume: 100 µL

Variant

Price:

$337.00

Quantity:

Ships: 1-2 business days

Product Details

Target

Fig4/Sac3

Scientific Background

Polyphosphoinositide phosphatase, SAC Domain-Containing Protein 3 or Fig4/Sac3 is encoded by the gene FIG4. Fig4/Sac3. The hydrolyzing phosphoinositide signals is involved with cell processes including intracellular membrane trafficking, exocytosis, endocytosis and membrane transport. Fig4/Sac3 is found widely in tissues. Diseases associated with this gene include Polymicrogyria, Yunis-Varon Syndrome and Charcot-Marie-Tooth Disease.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N202/7

Isotype

IgG1

Applications

ELISA, ICC, IHC, WB

Host Species

Mouse

Gene Name

Fig4 Kiaa0274 Sac3

Molecular Weight

100 kDa

Immunogen

Fusion protein amino acids 688-907 of mouse Sac3 (accession number Q91WF7) produced recombinantly in E. Coli

Immunogen Species

Mouse

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2104526

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Conjugate

Unconjugated

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Synonyms

Polyphosphoinositide phosphatase (EC 3.1.3.-) (Phosphatidylinositol 3,5-bisphosphate 5-phosphatase) (SAC domain-containing protein 3)

UniProt ID

Q91WF7

Shipping

Shipped on ice packs

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Anti-Fig4/Sac3 Antibody (N202/7)

SKU: 75-201

Product Details

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