Anti-FGF11/FHF3 Antibody (N92/14)

Name: Anti-FGF11/FHF3 Antibody
Brand: NeuroMab
SKU: 75-133
Price: 337.0 USD
Availability: InStock

Our mouse FGF11/FHF3 monoclonal antibody from NeuroMab is produced in-house from clone N92/14. It detects human, mouse, and rat FGF11/FHF3 and is purified by Protein A chromatography. Works in WB, ICC, IP, ELISA.

Transfected cell immunoblot: extracts of whole rat brain homogenate (WBH) and COS cells transfected with GFP-tagged FGF11/FHF3 and FGF13/FHF2 and untagged Kv2.1 plasmids and probed with N92/14 (left) and N52A/42 (right) TC supe.

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Species Reactivity

Human, Mouse, Rat

Applications

ELISA, ICC, IP, WB

Host Species

Mouse

Conjugates and Formulations

490

550

594

650

Biotin

Carrier-Free

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Data Sheet

SKU: 75-133

Volume: 100 µL

Variant

Price:

$337.00

Quantity:

Ships: 1-2 business days

Product Details

Target

FGF11/FHF3

Scientific Background

Fibroblast growth factor 11, FHF3 or FGF11 is encoded by the gene FGF11. FHF3 is a member of the fibroblast growth factor homologous factors family (a subfamily of fibroblast growth factors.). FHFs have a role in regulation of voltage fated sodium channels (Nav channels) and are thought to be involved in nervous system development. FHF3 is expressed in the Nervous system. Diseases associated with FGF11 include Congenital Myasthenic Syndrome 2A and Congenital Myasthenic Syndrome.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N92/14

Isotype

IgG2b

Applications

ELISA, ICC, IP, WB

Host Species

Mouse

Gene Name

FGF11 FHF3

Molecular Weight

25 kDa

Immunogen

Fusion protein amino acids 55-216 of human FGF11a (accession number Q92914) produced recombinantly in E. Coli

Immunogen Species

Human

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2103926

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.59

Conjugate

Unconjugated

Specificity

Does not cross-react with FGF12, FGF13 or FGF14 in heterologous cells

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Synonyms

Fibroblast growth factor 11 (FGF-11) (Fibroblast growth factor homologous factor 3) (FHF-3)

UniProt ID

Q92914

Shipping

Shipped on ice packs

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Anti-FGF11/FHF3 Antibody (N92/14)

SKU: 75-133

Product Details

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