Anti-DsbA-L (Disulfide-bond-A oxidoreductase-like protein) Antibody

Name: Anti-DsbA-L (Disulfide-bond-A oxidoreductase-like protein) Antibody
Brand: PhosphoSolutions
SKU: 465-DsbA-L
Price: 394.0 USD
Availability: InStock

Our Anti-DsbA-L (Disulfide-bond-A oxidoreductase-like protein) primary antibody from PhosphoSolutions is rabbit polyclonal. It detects human and mouse DsbA-L and is serum. It is great for use in WB, IHC.

Western blot of mouse adipose tissue lysate showing specific immunolabeling of the ~25 kDa DsbA-L protein.

Click on image to zoom

Species Reactivity

Human, Mouse

Applications

ELISA, IHC, WB

Host Species

Rabbit

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Data Sheet

Trial Size

SKU: 465-DsbA-L

Volume: 100 µL

Variant

Price:

$394.00

Quantity:

Ships: 1-2 business days

Product Details

Target

DsbA-L

Scientific Background

Disulfide-bond-A oxidoreductase-like protein (DsbA-L, previously named as GST Kappa) is an adiponectin-interacting protein. DsbA-L is highly expressed in adipose tissue, and its expression level is negatively correlated with obesity in mice and humans. DsbA-L expression in 3T3-L1 adipocytes is stimulated by the insulin sensitizer rosiglitazone and inhibited by the inflammatory cytokine TNFalpha. Polymorphism of DsbA-L gene has recently been implicated in insulin secretion and body fat distribution (Gao F et al., 2009). Overexpression of DsbA-L promotes adiponectin multimerization while suppressing DsbA-L expression by RNAi markedly and selectively reduces adiponectin levels and secretion in 3T3-L1 adipocytes. Recent studies identify DsbA-L as a key regulator for adiponectin biosynthesis (Liu et al., 2008).

Format

Serum

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, IHC, WB

Host Species

Rabbit

Gene Name

GSTK1

Molecular Weight

25 kDa

Immunogen

Full length recombinant mouse DsbA-L protein.

Immunogen Species

Mouse

Species Reactivity

Human, Mouse

Antibody Registry ID

AB_2492080

Storage

Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.

Physical State

Liquid

Production Notes

Serum

Buffer

Serum in 40% glycerol

Dilution Ranges

WB: 1:2000
IHC: 1:200

Conjugate

Unconjugated

Specificity

Specific for endogenous levels of the ~25 kDa DsbA-L protein. It is suggested that you add 1% BSA to the antibody dilution buffer.

Quality Control

Western blots performed on each lot.

Usage Statement

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Expiration

After date of receipt, stable for at least 1 year at -20°C.

Synonyms

DSBA like thioredoxin domain containing protein antibody, Glutathione S-transferase kappa 1, EC:2.5.1.18, GST 13-13, GST class-kappa, GST kappa, GSTK1-1, mGSTK1, Glutathione S-transferase subunit 13

UniProt ID

Q9DCM2

Shipping

Blue Ice

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Anti-DsbA-L (Disulfide-bond-A oxidoreductase-like protein) Antibody

SKU: 465-DsbA-L

Product Details

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