Anti-CDY1/2 Antibody (N143/38)

Name: Anti-CDY1/2 Antibody
Brand: NeuroMab
SKU: 75-174
Price: 337.0 USD
Availability: InStock

Our mouse CDY1/2 monoclonal antibody from NeuroMab is produced in-house from clone N143/38. It detects human CDY1/2 and is purified by Protein A chromatography. Works in WB, ICC, ELISA.

Transfected cell immunoblot: extracts of COS cells transiently transfected with GFP-tagged CDY1, HA- and Flag- tagged CDYL1 and CDYL2 and untagged Kv2.1 plasmids and probed with N143/38 (left panel), anti-Flag (middle panel) and K89/34 (right panel) TC supe.

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Species Reactivity

Human

Applications

ELISA, ICC, WB

Host Species

Mouse

Conjugates and Formulations

490

550

594

650

Biotin

Carrier-Free

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Data Sheet

SKU: 75-174

Volume: 100 µL

Variant

Price:

$337.00

Quantity:

Ships: 1-2 business days

Product Details

Target

CDY1/2

Scientific Background

This antibody recognizes the proteins Testis-specific chromodomain protein Y 1 and 2 and are encoded by the genes CDY1 and CDY2A respectively. These genes each have a paralog (CDY1B and CDY2B) which are also present on the Y chromosome. Proteins in the CDY-related family contain a chromodomain, involved in chromatin binding, and a histone acetyltransferase catalytic domain. These proteins are expressed in the nucleaus in testis. Diseases associated with these genes include Y-Linked Spermatogenic Failure, and Y Chromosome Infertility.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N143/38

Isotype

IgG1

Applications

ELISA, ICC, WB

Host Species

Mouse

Gene Name

CDY1 CDY1A; CDY1B

Molecular Weight

60 kDa

Immunogen

Fusion protein amino acids 6-66 (Chromo domain) of human CDY1 (accession number Q9Y6F8) produced recombinantly in E. Coli

Immunogen Species

Human

Species Reactivity

Human

Antibody Registry ID

AB_10673274

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.102

Conjugate

Unconjugated

Specificity

No cross-reactivity against CDYL1 or CDYL2

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Synonyms

Testis-specific chromodomain protein Y 1 (EC 2.3.1.48)

UniProt ID

Q9Y6F8

Shipping

Shipped on ice packs

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Anti-CDY1/2 Antibody (N143/38)

SKU: 75-174

Product Details

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