Anti-Cavß3 Calcium Channel Antibody Biotin Conjugate (N473/36)

Name: Anti-Cavß3 Calcium Channel Antibody Biotin Conjugate
Brand: NeuroMab
SKU: 75-472-BTN
Price: 543.0 USD
Availability: InStock

Our mouse Cavß3 calcium channel biotin conjugate monoclonal antibody from NeuroMab is produced in-house from clone N473/36. It detects human, mouse, and rat Cavß3 calcium channel and is purified by Protein A chromatography. Works in ELISA, ICC, WB.

Anti-Cavß3 Calcium Channel Antibody Biotin Conjugate

Click on image to zoom

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, ICC, WB

Host Species

Mouse

Conjugates and Formulations

Unconjugated

490

550

594

650

Carrier-Free

Go to Full Product Details

Data Sheet

SKU: 75-472-BTN

Volume: 200 µL

Variant

Price:

$543.00

Quantity:

Ships: 1-5 business days

Product Details

Target

Cavß3 calcium channel

Scientific Background

Voltage-dependent L-type calcium channel subunit beta-3 or Cav ß3 is encoded by the gene CACNB3. Cavß3 is a cytoplasmic subunit of voltage-sensitive calcium channels.These channels facilitate entry of calcium ions into excitable cells are involved in a variety of calcium dependent processes, including neurotransmitter release, muscle contraction, and gene expression. Cav ß3 is expressed in brain, colon and ovary. Diseases associated with this gene include Lambert-Eaton Myasthenic Syndrome.

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.3-0.5 mg/mL

Clonality

Monoclonal

Clone

N473/36

Isotype

IgG2b

Applications

ELISA, ICC, WB

Host Species

Mouse

Gene Name

CACNB3 CACNLB3

Molecular Weight

60 kDa

Immunogen

Fusion Protein Amino acids 20-149 (N-terminus) of human Cavbeta3 (accession number P54284)

Immunogen Species

Human

Species Reactivity

Human, Mouse, Rat

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

Biotin

Specificity

Does not cross-react with Cavbeta1, Cavbeta2 or Cavbeta4

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

CAB3; Voltage-dependent L-type calcium channel subunit beta-3; calcium channel; voltage-dependent; Calcium channel voltage-dependent subunit beta 3; beta 3 subunit

UniProt ID

P54284
UniProt Summary: Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents. Increases CACNA1B peak calcium current and shifts the voltage dependencies of channel activation and inactivation. Increases CACNA1C peak calcium current and shifts the voltage dependencies of channel activation and inactivation.

NCBI Gene ID

784

Shipping

Shipped on ice packs

Recover password

Create my account

Anti-Cavß3 Calcium Channel Antibody Biotin Conjugate (N473/36)

SKU: 75-472-BTN

Product Details

Bulk Order Anti-Cavß3 Calcium Channel Antibody Biotin Conjugate

Related Products

Recently Viewed