Anti-Cavß3 Calcium Channel Antibody (N473/36)

Name: Anti-Cavß3 Calcium Channel Antibody
Brand: NeuroMab
SKU: 75-472
Price: 337.0 USD
Availability: InStock

Our mouse Cavß3 calcium channel monoclonal antibody from NeuroMab is produced in-house from clone N473/36. It detects human, mouse, and rat Cavß3 calcium channel and is purified by Protein A chromatography. Works in WB, ICC, ELISA.

Immunoblot against extracts of COS cells transiently transfected with Myc¬Flag-tagged Cavbeta1, Cavbeta2, Cavbeta3, Cavbeta4 or untagged Kv2.1 plasmid probed with N473/86 (left) or mouse anti-Flag (right).

Immunoblot against extracts of COS cells transiently transfected with Myc¬Flag-tagged Cavbeta1, Cavbeta2, Cavbeta3, Cavbeta4 or untagged Kv2.1 plasmid probed with N473/86 (left) or mouse anti-Flag (right).

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Species Reactivity

Human, Mouse, Rat

Applications

ELISA, ICC, WB

Host Species

Mouse

Conjugates and Formulations

490

550

594

650

Biotin

Carrier-Free

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Data Sheet

SKU: 75-472

Volume: 100 µL

Variant

Price:

$337.00

Quantity:

Ships: 1-2 business days

Product Details

Target

Cavß3 calcium channel

Scientific Background

Voltage-dependent L-type calcium channel subunit beta-3 or Cav ß3 is encoded by the gene CACNB3. Cavß3 is a cytoplasmic subunit of voltage-sensitive calcium channels.These channels facilitate entry of calcium ions into excitable cells are involved in a variety of calcium dependent processes, including neurotransmitter release, muscle contraction, and gene expression. Cav ß3 is expressed in brain, colon and ovary. Diseases associated with this gene include Lambert-Eaton Myasthenic Syndrome.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N473/36

Isotype

IgG2b

Applications

ELISA, ICC, WB

Host Species

Mouse

Gene Name

CACNB3 CACNLB3

Molecular Weight

60 kDa

Immunogen

Fusion protein amino acids 20-149 (N-terminus) of human Cavbeta3 (accession number P54284)

Immunogen Species

Human

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2637017

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Conjugate

Unconjugated

Specificity

Does not cross-react with Cavbeta1, Cavbeta2 or Cavbeta4

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Synonyms

Voltage-dependent L-type calcium channel subunit beta-3 (CAB3) (Calcium channel voltage-dependent subunit beta 3)

UniProt ID

P54284

Shipping

Shipped on ice packs

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Anti-Cavß3 Calcium Channel Antibody (N473/36)

SKU: 75-472

Product Details

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