Anti-Brevican Antibody (N294A/6)

Name: Anti-Brevican Antibody
Brand: NeuroMab
SKU: 75-281
Price: 337.0 USD
Availability: InStock

Our mouse Brevican monoclonal antibody from NeuroMab is produced in-house from clone N294A/6. It detects mouse and rat Brevican and is purified by Protein A chromatography. Works in WB, IHC, ICC, ELISA.

Immunoblot versus crude membrane preparations from adult rat brain (RBM) and Brevican wild-type (WT) and knockout (KO) mice and probed with N294A/6 (left) and N52A/42 (right) TC supe. Mouse brain samples courtesy of Matthew Rasband, Baylor College of Medicine.

Click on image to zoom

Species Reactivity

Mouse, Rat

Applications

ELISA, ICC, IHC, WB

Host Species

Mouse

Conjugates and Formulations

490

550

594

650

Biotin

Carrier-Free

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Data Sheet

KO Validated

SKU: 75-281

Volume: 100 µL

Variant

Price:

$337.00

Quantity:

Ships: 1-2 business days

Product Details

Target

Brevican

Scientific Background

Brevican core protein, Chondroitin sulfate proteoglycan 7 or Brain-enriched hyaluronan-binding protein is encoded by the gene BCAN and is a member of the lectican family of chondroitin sulfate proteoglycans. Brevican is involved in the development and formation of the brain extracellular matrix and may be involved in malignancy of brain tumor cells. Brevican is developmentally regulated and specifically expressed in the central nervous system. Diseases associated with this gene include Low-Grade Astrocytoma.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N294A/6

Isotype

IgG2b

Applications

ELISA, ICC, IHC, WB

Host Species

Mouse

Gene Name

Bcan Behab

Molecular Weight

140 kDa (and smaller due to proteolytic cleavage)

Immunogen

Fusion protein amino acids 219-655 of rat Brevican (accession number P55068) produced recombinantly in E. Coli

Immunogen Species

Rat

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_2315822

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Conjugate

Unconjugated

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Synonyms

Brevican core protein (Brain-enriched hyaluronan-binding protein) (BEHAB)

UniProt ID

P55068

Shipping

Shipped on ice packs

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Anti-Brevican Antibody (N294A/6)

SKU: 75-281

Product Details

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