Anti-BKbeta3a K+ Channel Antibody FL490 Conjugate (N40B/18)

Name: Anti-BKbeta3a K+ Channel Antibody FL490 Conjugate
Brand: NeuroMab
SKU: 75-098-FL490
Price: 486.0 USD
Availability: InStock

Our mouse BKbeta3a K+ channel FL490 conjugate monoclonal antibody from NeuroMab is produced in-house from clone N40B/18. It detects human, mouse, and rat BKbeta3a K+ channel and is purified by Protein A chromatography. Works in IHC.

Anti-BKbeta3a K+ Channel Antibody FL490 Conjugate

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Species Reactivity

Human, Mouse, Rat

Applications

IHC

Host Species

Mouse

Conjugates and Formulations

Unconjugated

550

594

650

Biotin

Carrier-Free

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Data Sheet

SKU: 75-098-FL490

Volume: 200 µL

Variant

Price:

$486.00

Quantity:

Ships: 1-5 business days

Product Details

Target

BKbeta3a K+ channel

Scientific Background

Calcium-activated potassium channel subunit beta-3, Potassium Calcium-Activated Channel Subfamily M Regulatory Beta Subunit 3 or BKBeta3a is encoded by the gene KCNMB3. BKbeta3a can bind to KCNMA1 to form a channel in the calcium activated large conductance (MaxiK channel) family. BKbeta3a acts to modulate the calcium sensitivity and gating kinetics of KCNMA1. It is widely expressed in tissues, and is present in several isoforms. Diseases associated with this gene include Familial Febrile Seizures.

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.3-0.5 mg/mL

Clonality

Monoclonal

Clone

N40B/18

Isotype

IgG1

Applications

IHC

Host Species

Mouse

Gene Name

Kcnmb3

Molecular Weight

32 kDa

Immunogen

Fusion protein amino acids 1-49 (unique N-terminus) of mouse BKBeta3a (accession number Q08460) produced recombinantly in E. Coli

Immunogen Species

Mouse

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2939364

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL490 Ex: 491 nm, Em: 515 nm

Specificity

No cross-reactivity against BKBeta1, BKBeta2, BKBeta3b or BKBeta4

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

Potassium large conductance calcium-activated channel, subfamily M, beta member 3

UniProt ID

Q08460

Shipping

Shipped on ice packs

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Anti-BKbeta3a K+ Channel Antibody FL490 Conjugate (N40B/18)

SKU: 75-098-FL490

Product Details

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