Anti-BKbeta3a K+ Channel Antibody Biotin Conjugate (N40B/18)

Name: Anti-BKbeta3a K+ Channel Antibody Biotin Conjugate
Brand: NeuroMab
SKU: 75-098-BTN
Price: 543.0 USD
Availability: InStock

Our mouse BKbeta3a K+ channel biotin conjugate monoclonal antibody from NeuroMab is produced in-house from clone N40B/18. It detects human, mouse, and rat BKbeta3a K+ channel and is purified by Protein A chromatography. Works in ELISA, IHC, WB, IP.

Anti-BKbeta3a K+ Channel Antibody Biotin Conjugate

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Species Reactivity

Human, Mouse, Rat

Applications

ELISA, IHC, IP, WB

Host Species

Mouse

Conjugates and Formulations

Unconjugated

490

550

594

650

Carrier-Free

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Data Sheet

SKU: 75-098-BTN

Volume: 200 µL

Variant

Price:

$543.00

Quantity:

Ships: 1-5 business days

Product Details

Target

BKbeta3a K+ channel

Scientific Background

Calcium-activated potassium channel subunit beta-3, Potassium Calcium-Activated Channel Subfamily M Regulatory Beta Subunit 3 or BKBeta3a is encoded by the gene KCNMB3. BKbeta3a can bind to KCNMA1 to form a channel in the calcium activated large conductance (MaxiK channel) family. BKbeta3a acts to modulate the calcium sensitivity and gating kinetics of KCNMA1. It is widely expressed in tissues, and is present in several isoforms. Diseases associated with this gene include Familial Febrile Seizures.

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.3-0.5 mg/mL

Clonality

Monoclonal

Clone

N40B/18

Isotype

IgG1

Applications

ELISA, IHC, IP, WB

Host Species

Mouse

Gene Name

Kcnmb3

Molecular Weight

32 kDa

Immunogen

Fusion Protein Amino acids 1-49 (unique N-terminus) of mouse BKBeta3a (accession number Q08460) produced recombinantly in E. Coli

Immunogen Species

Mouse

Species Reactivity

Human, Mouse, Rat

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

Biotin

Specificity

No cross-reactivity against BKBeta1, BKBeta2, BKBeta3b or BKBeta4

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

Potassium large conductance calcium-activated channel, subfamily M, beta member 3

UniProt ID

Q08460

Shipping

Shipped on ice packs

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Anti-BKbeta3a K+ Channel Antibody Biotin Conjugate (N40B/18)

SKU: 75-098-BTN

Product Details

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