Anti-Basic Fibroblast growth factor (Basic FGF) Antibody

Name: Anti-Basic Fibroblast growth factor (Basic FGF) Antibody
Brand: Biosensis
SKU: S-008-100
Price: 327.0 USD
Availability: InStock

Our Anti-Basic Fibroblast growth factor (Basic FGF) sheep polyclonal primary antibody detects human, mouse, and rat Basic Fibroblast growth factor (Basic FGF), and is whole serum. It is validated for use in IHC-Frozen, WB.

Species Reactivity

Human, Mouse, Rat

Applications

IHC, WB

Host Species

Sheep

Go to Full Product Details

Data Sheet

SKU: S-008-100

Volume/Size: 100 µL

Variant

Price:

$327.00

Quantity:

Product Details

Target

Basic Fibroblast growth factor (Basic FGF)

Scientific Background

Fibroblast growth factors (FGFs), a heparin binding growth factor, exhibit widespread mitogenic and neurotrophic activities in a variety of different cells including mesenchymal, neuroectodermal and endothelial cells. aFGF (FGF-1) and bFGF (FGF-2) are present in relatively high levels in CNS. aFGF is expressed by a subset of neuronal populations, while bFGF is expressed by astrocytes, both lack signal peptides. Human bFGF is a 17.2 kDa protein containing 155 amino acid residues. FUNCTION: The heparin-binding growth factors are angiogenic agents in vivo and are potent mitogens for a variety of cell types in vitro. There are differences in the tissue distribution and concentration of these 2 growth factors. SUBUNIT: Monomer. Interacts with CSPG4 and FGFBP1. Found in a complex with FGFBP1, FGF1 and FGF2. MISCELLANEOUS: This protein binds heparin more strongly than does aFGF. SIMILARITY: Belongs to the heparin-binding growth factors family.

Format

Whole serum

Clonality

Polyclonal

Isotype

Mixed

Applications

IHC, WB

Host Species

Sheep

Immunogen

Recombinant human basic FGF

Immunogen Species

Human

Species Reactivity

Human, Mouse, Rat

Storage

Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material. After reconstitution keep aliquots at -20°C for a higher stability, and at 2-8°C with an appropriate antibacterial agent. Glycerol (1:1) may be added for an additional stability. Avoid repetitive freeze/thaw cycles.

Physical State

Lyophilized

Dilution Ranges

WB: 1:1000-1:2000
IHC: 1:1000-1:2000

Conjugate

Unconjugated

Specificity

A high level of specificity for bFGF was shown by immunohistochemistry for this antiserum. This antibody is known to react with human, mouse and rat basic FGF.

Usage Statement

For research use only.

Country of Origin

United States

Expiration

Store at 2-8°C for up to 3 months. For longer storage, aliquot and store at -20°C for up to 12 months.

Synonyms

Heparin-binding growth factor 2; HBGF-2; Basic fibroblast growth factor; bFGF; Prostatropin; FGF2; FGFB

UniProt ID

P09038

Shipping

25°C (ambient)

Recover password

Create my account

Anti-Basic Fibroblast growth factor (Basic FGF) Antibody

SKU: S-008-100

Product Details

Bulk Order Anti-Basic Fibroblast growth factor (Basic FGF) Antibody

Related Products

Recently Viewed