Anti-Ankyrin-G (Staining) Antibody (BSA and Azide free) (N106/36)

Name: Anti-Ankyrin-G (Staining) Antibody (BSA and Azide free)
Brand: NeuroMab
SKU: 75-146-CF
Price: 486.0 USD
Availability: InStock

Our mouse Ankyrin-G (Staining) carrier-free monoclonal antibody from NeuroMab is produced in-house from clone N106/36. It detects feline, hamster, human, mouse, non-human primate, and rat Ankyrin-G (Staining) and is purified by Protein A chromatography. Works in WB, IHC, ICC, ELISA.

Anti-Ankyrin-G (Staining) Antibody (BSA and Azide free)

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Species Reactivity

Feline, Hamster, Human, Mouse, Non-Human Primate, Rat

Applications

ELISA, ICC, IHC, WB

Host Species

Mouse

Conjugates and Formulations

Unconjugated

490

550

594

650

Biotin

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Data Sheet

SKU: 75-146-CF

Volume: 100 µL

Variant

Price:

$486.00

Quantity:

Ships: 1-5 business days

Product Details

Target

Ankyrin-G (Staining)

Scientific Background

Ankyrin-G (ankyrin 3) is a member of the Ankyrin family which consists of Ankyrin R (1), Ankyrin B (2) and Ankyrin G (3) all of which are expressed in the nervous system. Ankyrins are structural proteins that aid in the attachment of integral membrane proteins with the spectrin-actin cytoskeleton, and thus targets voltage-gated sodium channels, potassium channels, cell adhesion molecules and others at the nodes of Ranvier and axonal initial segments (AIS). Variants in Ankyrin G have been linked to bipolar disorder.

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.6-1.0 mg/mL

Clonality

Monoclonal

Clone

N106/36

Isotype

IgG2a

Applications

ELISA, ICC, IHC, WB

Host Species

Mouse

Gene Name

ANK3

Molecular Weight

<200 kDa

Immunogen

Fusion protein ~1000 amino acids of Ankyrin-G (accession number E9PE32) produced recombinantly in E. Coli

Immunogen Species

Human

Species Reactivity

Feline, Hamster, Human, Mouse, Non-Human Primate, Rat

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and buffer exchanged into 1X PBS. Purified mAbs are >90% specific antibody.

Buffer

PBS

Conjugate

Unconjugated

Specificity

Does not cross-react with Ankyrin-B

Quality Control

Each new lot of antibody is quality control tested by IHC on either rat or mouse brain and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

Ankyrin-3 (ANK-3) (Ankyrin-G)

UniProt ID

E9PE32

Shipping

Shipped on ice packs

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Anti-Ankyrin-G (Staining) Antibody (BSA and Azide free) (N106/36)

SKU: 75-146-CF

Product Details

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