Anti-Ankyrin-B Antibody (N105/13)

Name: Anti-Ankyrin-B Antibody
Brand: NeuroMab
SKU: 75-144
Price: 394.0 USD
Availability: InStock

Our mouse Ankyrin-B monoclonal antibody from NeuroMab is produced in-house from clone N105/13. It detects bovine, guinea pig, human, mouse, and rat Ankyrin-B and is purified by Protein A chromatography. Works in WB, IHC, ICC, IP, ELISA.

Adult rat hippocampus immunohistochemistry.

Adult rat hippocampus immunohistochemistry.

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Species Reactivity

Bovine, Guinea Pig, Human, Mouse, Rat

Applications

ELISA, ICC, IHC, IP, WB

Host Species

Mouse

Conjugates and Formulations

490

550

594

650

Biotin

Carrier-Free

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Data Sheet

SKU: 75-144

Volume: 100 µL

Variant

Price:

$394.00

Quantity:

Ships: 1-2 business days

Product Details

Target

Ankyrin-B

Scientific Background

Ankyrin-2 or -Ankyrin-B is encoded by the gene ANK2. Ankyrin B is a scaffold protein that functions to link proteins that mediate the attachment of integral membrane proteins to the spectrin-actin based membrane cytoskeleton. In this manner, ankyrin family proteins play key roles in various processes including cell motility, activation, proliferation, contact and the maintenance of specialized membrane domains. Ankyrin B is expressed in brain and muscle. Mutations in this gene cause long QT syndrome 4 and cardiac arrhythmia syndrome.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N105/13

Isotype

IgG1

Applications

ELISA, ICC, IHC, IP, WB

Host Species

Mouse

Gene Name

ANK2 ANKB

Molecular Weight

>200 kDa

Immunogen

Fusion protein amino acids 203-496 of human Ankyrin-B (accession number Q01484) produced recombinantly in E. Coli

Immunogen Species

Human

Species Reactivity

Bovine, Guinea Pig, Human, Mouse, Rat

Antibody Registry ID

AB_10673094

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.70

Dilution Ranges

WB: 1:500
IHC: 1:500
ICC: 1:500
IP: 3 ug

Conjugate

Unconjugated

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Synonyms

Ankyrin-2 (ANK-2) (Ankyrin-B) (Brain ankyrin) (Non-erythroid ankyrin)

UniProt ID

Q01484

Shipping

Shipped on ice packs

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Anti-Ankyrin-B Antibody (N105/13)

SKU: 75-144

Product Details

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