Anti-KLK-L3 (KLK9) Antibody

Name: Anti-KLK-L3 (KLK9) Antibody
Brand: PhosphoSolutions
SKU: 24236
Price: 456.0 USD
Availability: InStock

Our KLK9 rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It detects human KLK9 and is antigen affinity purified. It is great for use in WB.

Western Blot of cancer cell lines LnNCap (lane 1) and BT-474 (lane 2) showing specific immunolabeling of KLK-L3.

Click on image to zoom

Species Reactivity

Human

Applications

ELISA, WB

Host Species

Rabbit

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Data Sheet

SKU: 24236

Title: 100 µL

Variant

Price:

$456.00

Quantity:

Ships: 1-2 business days

Product Details

Target

KLK9

Scientific Background

Kallikreins are a subgroup of serine proteases and are implicated in carcinogenesis. (KLK-L3; HGMW-approved symbol KLK9) is a novel kallikrein gene with utility for diagnosis, monitoring and therapeutics of various cancers including those of the breast, prostate and testis.

Format

Antigen Affinity Purified

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB

Host Species

Rabbit

Gene Name

KLK9

Immunogen

Synthetic peptide corresponding to amino acids from the C-terminal region of human KLK9 protein

Immunogen Species

Human

Species Reactivity

Human

Storage

Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.

Physical State

Liquid

Buffer

PBS + 0.02% NaN3

Dilution Ranges

WB: 1:500-1:1000
WB Brain: 1:500-1:1000

Specificity

Reacts with the C-terminal region of the human KLK-L3 (KLK9) protein.

Quality Control

Western blots performed on each lot.

Usage Statement

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Country of Origin

United States

Expiration

After date of receipt, stable for at least 1 year at -20°C.

Synonyms

KLK-L3; Kallikrein-like protein 3; kallikrein-9

UniProt ID

Q9UKQ9
UniProt Summary: Serine protease which exhibits a preference for Arg over Lys in the substrate P1 position and for Ser or Pro in the P2 position. Shows activity against amyloid precursor protein, myelin basic protein, gelatin, casein and extracellular matrix proteins such as fibronectin, laminin, vitronectin and collagen. Degrades alpha-synuclein and prevents its polymerization, indicating that it may be involved in the pathogenesis of Parkinson disease and other synucleinopathies. May be involved in regulation of axon outgrowth following spinal cord injury. Tumor cells treated with a neutralizing KLK6 antibody migrate less than control cells, suggesting a role in invasion and metastasis.

NCBI Gene ID

284366

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Anti-KLK-L3 (KLK9) Antibody

SKU: 24236

Product Details

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