Anti-Hormone-sensitive lipase (HSL) Antibody

Name: Anti-Hormone-sensitive lipase (HSL) Antibody
Brand: Biosensis
SKU: C-1523-500
Price: 347.0 USD
Availability: InStock

Our Anti-Hormone-sensitive lipase (HSL) chicken polyclonal primary antibody detects human, mouse, and rat Hormone-sensitive lipase (HSL), and is affinity-purified. It is validated for use in WB.

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Species Reactivity

Human, Mouse, Rat

Applications

Host Species

Chicken

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Data Sheet

SKU: C-1523-500

Volume/Size: 500 µL

Variant

Price:

$347.00

Quantity:

Ships: 1-2 business days

Product Details

Target

Hormone-sensitive lipase (HSL)

Scientific Background

Hormone Sensitive Lipase (HSL) hydrolyzes stored triglycerides to free fatty acids in adipose tissue and heart. In steroidogenic tissues, HSL principally converts cholesteryl esters to free cholesterol for steroid hormone production (ref: SWISSPROT).

Format

Affinity-purified

Clonality

Polyclonal

Isotype

IgY

Applications

Host Species

Chicken

Molecular Weight

83 kDa

Immunogen

Mouse Hormone Sensitive Lipase mixed peptides (617-828, 533-544, 191-202 aa).

Immunogen Species

Mouse

Species Reactivity

Human, Mouse, Rat

Storage

Short term storage at 2-8°C for one week. At -20°C as an undiluted liquid for up to 12 months.

Physical State

Liquid

Buffer

PBS with 0.02% sodium azide.

Dilution Ranges

WB: 1:1000-1:5000

Conjugate

Unconjugated

Specificity

This antibody detects HSL at approx 83 kDa in various fat cell lysates from mouse and rat. Additional weaker band may appear at approx 40 kDa (unknown). mouse, rat, Human.

Usage Statement

For research use only.

Country of Origin

United States

Expiration

12 months after date of receipt (unopened vial).

Synonyms

4933403G17Rik; HSL; hormone-sensitive lipase; LIPE

UniProt ID

P54310
UniProt Summary: Lipase with broad substrate specificity, catalyzing the hydrolysis of triacylglycerols (TAGs), diacylglycerols (DAGs), monoacylglycerols (MAGs), cholesteryl esters and retinyl esters. Shows a preferential hydrolysis of DAGs over TAGs and MAGs and preferentially hydrolyzes the fatty acid (FA) esters at the sn-3 position of the glycerol backbone in DAGs. Preferentially hydrolyzes FA esters at the sn-1 and sn-2 positions of the glycerol backbone in TAGs. Catalyzes the hydrolysis of 2-arachidonoylglycerol, an endocannabinoid and of 2-acetyl monoalkylglycerol ether, the penultimate precursor of the pathway for de novo synthesis of platelet-activating factor. In adipose tissue and heart, it primarily hydrolyzes stored triglycerides to free fatty acids, while in steroidogenic tissues, it principally converts cholesteryl esters to free cholesterol for steroid hormone production.

NCBI Gene ID

16890

Shipping

2-8°C (on cold packs)

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Anti-Hormone-sensitive lipase (HSL) Antibody

SKU: C-1523-500

Product Details

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