Anti-ElF5a2 Antibody

Name: Anti-ElF5a2 Antibody
Brand: PhosphoSolutions
SKU: 24227
Price: 456.0 USD
Availability: InStock

Our EIF5a2 rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It detects human, mouse, and rat EIF5a2 and is antigen affinity purified. It is great for use in WB.

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, WB

Host Species

Rabbit

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Data Sheet

SKU: 24227

Title: 100 µL

Variant

Price:

$456.00

Quantity:

Ships: 1-2 business days

Product Details

Target

EIF5a2

Scientific Background

Eukaryotic translation initiation factor 5A (eIF5A) is an essential protein tightly linked to cellular polyamine homeostasis. EIF5A2 is a novel phylogenetically conserved gene for eIF5A and localized in an area of the genome often noted for chromosomal instability in cancers. EIF5A2 expression has been observed in testis, brain and colorectal adenocarcinoma.

Format

Antigen Affinity Purified

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB

Host Species

Rabbit

Gene Name

EIF5A2

Immunogen

Synthetic peptide corresponding to amino acids from the C-terminal region of human EIF5a2 protein.

Immunogen Species

Human

Species Reactivity

Human, Mouse, Rat

Storage

Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.

Physical State

Liquid

Buffer

PBS + 0.02% NaN3

Dilution Ranges

WB: 1:500-1:1000
WB Brain: 1:500-1:1000

Specificity

Reacts with the C-terminal region of the 17 kDa human, mouse and rat EIF5A2 protein.

Quality Control

Western blots performed on each lot.

Usage Statement

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Country of Origin

United States

Expiration

After date of receipt, stable for at least 1 year at -20°C.

Synonyms

EIF-5A2; Eukaryotic translation initiation factor 5A-2; eIF-5A-2; eukaryotic initiation factor 5A

UniProt ID

Q9GZV4
UniProt Summary: Translation factor that promotes translation elongation and termination, particularly upon ribosome stalling at specific amino acid sequence contexts. Binds between the exit (E) and peptidyl (P) site of the ribosome and promotes rescue of stalled ribosome: specifically required for efficient translation of polyproline-containing peptides as well as other motifs that stall the ribosome. Acts as a ribosome quality control (RQC) cofactor by joining the RQC complex to facilitate peptidyl transfer during CAT tailing step. Also involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity.

NCBI Gene ID

56648

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Anti-ElF5a2 Antibody

SKU: 24227

Product Details

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