Anti-CRTR1 Antibody

Name: Anti-CRTR1 Antibody
Brand: PhosphoSolutions
SKU: 24220
Price: 456.0 USD
Availability: InStock

Our CRTR1 rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It detects human CRTR1 and is antigen affinity purified. It is great for use in WB.

Species Reactivity

Human

Applications

ELISA, WB

Host Species

Rabbit

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Data Sheet

SKU: 24220

Title: 100 µL

Variant

Price:

$456.00

Quantity:

Ships: 1-2 business days

Product Details

Target

CRTR1

Scientific Background

CP2-related proteins are a family of DNA-binding transcription factors that are generally activators of transcription and expressed ubiquitously. A novel CP2 family member, CP2-Related Transcriptional Repressor-1 (CRTR-1), is expressed in a developmentally regulated fashion in vivo and acts as a direct repressor of transcription

Format

Antigen Affinity Purified

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB

Host Species

Rabbit

Gene Name

TFCP2L1

Immunogen

Synthetic peptide corresponding to amino acids from the N-terminal and C-terminal regions of human CRTR1 protein

Immunogen Species

Human

Species Reactivity

Human

Storage

Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.

Physical State

Liquid

Buffer

PBS + 0.02% NaN3

Dilution Ranges

WB: 1:500-1:1000
WB Brain: 1:500-1:1000

Specificity

Reacts with the N-terminal (part of the region responsible for CRTR-1-mediated transcriptional repression) and C-terminal regions of the human CRTR-1 protein.

Quality Control

Western blots performed on each lot.

Usage Statement

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Country of Origin

United States

Expiration

After date of receipt, stable for at least 1 year at -20°C.

Synonyms

CRTR1; TFCP2L1; LBP9; transcription factor CP2-like protein 1; CP2-related transcriptional repressor 1; CRTR-1; transcription factor LBP-9; CP2 related transcriptional repressor 1; transcription factor CP2 like protein 1

UniProt ID

Q9NZI6
UniProt Summary: Transcription factor that facilitates establishment and maintenance of pluripotency in embryonic stem cells (ESCs). With KLF2, acts as the major effector of self-renewal that mediates induction of pluripotency downstream of LIF/STAT3 and Wnt/beta-catenin signaling. Required for normal duct development in the salivary gland and kidney. Coordinates the development of the kidney collecting ducts intercalated (IC) and principal (PC) cells, which regulate acid-base and salt-water homeostasis, respectively. Regulates the expression of IC genes including subunits B1 and D2 of the V-ATPase complex, OXGR1, CA12, SLC4A1, AQP6 and IC-specific transcription factor FOXI1. Also regulates the expression of JAG1 and subsequent notch signaling in the collecting duct. JAG1 initiates notch signaling in PCs but inhibits notch signaling in ICs. Acts as a transcriptional suppressor that may suppress UBP1-mediated transcriptional activation. Modulates the placental expression of CYP11A1.

NCBI Gene ID

29842

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Anti-CRTR1 Antibody

SKU: 24220

Product Details

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