Anti-CD72 (C-terminus) Antibody

Name: Anti-CD72 (C-terminus) Antibody
Brand: PhosphoSolutions
SKU: 24200
Price: 456.0 USD
Availability: InStock

Our CD72 rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It detects human CD72 and is antigen affinity purified. It is great for use in WB.

Species Reactivity

Human

Applications

ELISA, WB

Host Species

Rabbit

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Data Sheet

SKU: 24200

Title: 100 µL

Variant

Price:

$456.00

Quantity:

Ships: 1-2 business days

Product Details

Target

CD72

Scientific Background

CD72 is a lymphocyte receptor for the Class IV semaphorin CD100, which is involved in regulating B cell signaling.

Format

Antigen Affinity Purified

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB

Host Species

Rabbit

Gene Name

CD72

Immunogen

Synthetic peptide corresponding to amino acids from the C-terminal region of human CD72 protein.

Immunogen Species

Human

Species Reactivity

Human

Storage

Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.

Physical State

Liquid

Buffer

PBS + 0.02% NaN3

Dilution Ranges

WB: 1:500-1:1000
WB Brain: 1:500-1:1000

Specificity

Reacts with the C-terminal region of 42 kDa human CD72 protein.

Quality Control

Western blots performed on each lot.

Usage Statement

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Country of Origin

United States

Expiration

After date of receipt, stable for at least 1 year at -20°C.

Synonyms

CD72b; B cell differentiation antigen CD72; B-cell differentiation antigen CD72; CD72 antigen; lyb-2; Ly 19; Ly 32; LYB2; Lymphocyte antigen 32

UniProt ID

P21854
UniProt Summary: Co-receptor of B cell receptor (BCR) that plays both positive and negative roles on B-cell functions. Recognizes the Sm/ribonucleoprotein (RNP) self-antigen ligand, and coligation of CD72 and BCR inhibits BCR signaling. Mechanistically, ligand binding leads to the recruitment of PTPN6/SHP-1 to the BCR complex which is inhibitory to BCR signaling. Also acts as a ligand for CD5 and thereby plays a critical role in maintaining regulatory T and B-cell homeostasis.

NCBI Gene ID

971

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Anti-CD72 (C-terminus) Antibody

SKU: 24200

Product Details

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