Anti-Cavß3 Calcium Channel Antibody FL490 Conjugate (N473/36)

Name: Anti-Cavß3 Calcium Channel Antibody FL490 Conjugate
Brand: NeuroMab
SKU: 75-472-FL490
Price: 486.0 USD
Availability: InStock

Our mouse Cavß3 calcium channel FL490 conjugate monoclonal antibody from NeuroMab is produced in-house from clone N473/36. It detects human, mouse, and rat Cavß3 calcium channel and is purified by Protein A chromatography. Works in ICC.

Anti-Cavß3 Calcium Channel Antibody FL490 Conjugate

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Species Reactivity

Human, Mouse, Rat

Applications

ICC

Host Species

Mouse

Conjugates and Formulations

Unconjugated

550

594

650

Biotin

Carrier-Free

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Data Sheet

SKU: 75-472-FL490

Volume: 200 µL

Variant

Price:

$486.00

Quantity:

Ships: 1-5 business days

Product Details

Target

Cavß3 calcium channel

Scientific Background

Voltage-dependent L-type calcium channel subunit beta-3 or Cav ß3 is encoded by the gene CACNB3. Cavß3 is a cytoplasmic subunit of voltage-sensitive calcium channels.These channels facilitate entry of calcium ions into excitable cells are involved in a variety of calcium dependent processes, including neurotransmitter release, muscle contraction, and gene expression. Cav ß3 is expressed in brain, colon and ovary. Diseases associated with this gene include Lambert-Eaton Myasthenic Syndrome.

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.3-0.5 mg/mL

Clonality

Monoclonal

Clone

N473/36

Isotype

IgG2b

Applications

ICC

Host Species

Mouse

Gene Name

CACNB3 CACNLB3

Molecular Weight

60 kDa

Immunogen

Fusion protein amino acids 20-149 (N-terminus) of human Cavbeta3 (accession number P54284)

Immunogen Species

Human

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2940576

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL490 Ex: 491 nm, Em: 515 nm

Specificity

Does not cross-react with Cavbeta1, Cavbeta2 or Cavbeta4

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

Voltage-dependent L-type calcium channel subunit beta-3 (CAB3) (Calcium channel voltage-dependent subunit beta 3)

UniProt ID

P54284

Shipping

Shipped on ice packs

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Anti-Cavß3 Calcium Channel Antibody FL490 Conjugate (N473/36)

SKU: 75-472-FL490

Product Details

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