Non-specific Control IgG Antibody (Saporin) (X63)
Our Non-Specific Control IgG Antibody (Saporin) mouse monoclonal primary antibody is a purified, non-reactive, negative control.
SKU: M-1792-100-IT
Ships: 1-2 business days
Product Details
Isotype control
Purified
Monoclonal
X63
AT
Mouse
Unknown, naturally isolated IgG that has no known binding target in mammals
Species Independent
Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water to achieve a conjugate concentration of 1 mg/mL. Centrifuge to remove any insoluble material. Final buffer contains no preservatives.Lyophilized product is shipped at ambient room temperature. Upon receipt, pulse-centrifuge the vial to collect solid that may be entrapped in the lid. After reconstitution, immediately prepare aliquots and keep the undiluted stock at -80°C for long-term storage. Avoid repeated thaw-freezing. For short-term storage, keep at 2-8°C for up to 2 weeks. it is recommended to handle this product under sterile conditions.
Lyophilized
Conjugate was purified by ion-exchange chromatography. Purity > 90% by non-reducing SDS-PAGE
Lyophilized from a 1 mg/mL solution containing PBS pH 7.2-7.6 without preservative.
Negative control for targeting IgG1-saporin conjugates., for instance MC192-saporin. X63-saporin should be used at a concentration equal to that of the test antibody-saporin conjugate.
Unconjugated
No staining has ever been identified with this immunoglobulin demonstrating its non-specific value as a control.
For research use only.
United States
12 months after date of receipt (unopened vial).
P20656
UniProt Summary: Constant region of immunoglobulin light chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens. The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen.
UniProt Summary: Constant region of immunoglobulin light chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens. The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen.
25°C (ambient)

