Anti-Neurokinin-3 Receptor (NK-3R) Antibody

Name: Anti-Neurokinin-3 Receptor (NK-3R) Antibody
Brand: Biosensis
SKU: R-103-100
Price: 327.0 USD
Availability: InStock

Our Anti-Neurokinin-3 Receptor (NK-3R) rabbit polyclonal primary antibody detects rat Neurokinin-3 Receptor (NK-3R), and is whole serum. It is validated for use in WB.

Species Reactivity

Rat

Applications

Host Species

Rabbit

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Data Sheet

SKU: R-103-100

Volume/Size: 100 µL

Variant

Price:

$327.00

Quantity:

Product Details

Target

Neurokinin-3 Receptor (NK-3R)

Scientific Background

FUNCTION: This is a receptor for the tachykinin neuropeptide neuromedin K (neurokinin B). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. SUBCELLULAR LOCATION: Membrane; multi-pass membrane protein. PTM: The anchoring of this receptor to the plasma membrane is probably mediated by the palmitoylation of a cysteine residue. MISCELLANEOUS: The rank order of affinity of this receptor to tachykinins is: neuromedin K > substance K > substance P. SIMILARITY: Belongs to the G-protein coupled receptor 1 family.

Format

Whole serum

Clonality

Polyclonal

Isotype

Mixed

Applications

Host Species

Rabbit

Molecular Weight

66 kDa

Immunogen

A synthetic peptide (ASTTSSF ISSPYTSVDE YS) corresponding to the absolute C-terminal of rat NK-3 receptor protein (aa: 434-452) conjugated to KLH

Immunogen Species

Rat

Species Reactivity

Rat

Storage

Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material. After reconstitution keep aliquots at -20°C for a higher stability, and at 2-8°C with an appropriate antibacterial agent. Glycerol (1:1) may be added for an additional stability. Avoid repetitive freeze/thaw cycles.

Physical State

Lyophilized

Dilution Ranges

WB: 1:500-1:2000

Conjugate

Unconjugated

Specificity

Specificity has been shown by Western blot using rat brain homogenate. A band of 66 kDa, the theoretical MW of NK-3R, could be easily detected. This antiserum is know to cross react with rat NK-3 R.

Usage Statement

For research use only.

Country of Origin

United States

Expiration

12 months after date of receipt (unopened vial).

Synonyms

Neuromedin K receptor; NKR; Neurokinin B receptor; NK-3 receptor; NK-3R; Tachykinin receptor 3; Tacr3; Tac3r

UniProt ID

P16177

Shipping

25°C (ambient)

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Anti-Neurokinin-3 Receptor (NK-3R) Antibody

SKU: R-103-100

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