Anti-GFR alpha-2 Antibody

Name: Anti-GFR alpha-2 Antibody
Brand: Biosensis
SKU: R-067-100
Price: 337.0 USD
Availability: InStock

Our Anti-Glial cell-derived neurotrophic factor receptor alpha-2 (GFR alpha-2) rabbit polyclonal primary antibody detects human and rat Glial cell-derived neurotrophic factor receptor alpha-2 (GFR alpha-2), and is whole serum. It is validated for use in IHC-Frozen, WB.

Immunohistochemical staining of rat dorsal root ganglia using Rabbit antibody to to GFR alpha-2 (376-390): whole serum, catalogue no. R-067-100.

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Species Reactivity

Human, Rat

Applications

IHC, WB

Host Species

Rabbit

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Data Sheet

SKU: R-067-100

Volume/Size: 100 µL

Variant

Price:

$337.00

Quantity:

Product Details

Target

Glial cell-derived neurotrophic factor receptor alpha-2 (GFR alpha-2)

Scientific Background

FUNCTION: Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor. SUBCELLULAR LOCATION: Cell membrane; lipid-anchor; GPI-anchor (By similarity). ALTERNATIVE PRODUCTS: 2 named isoforms produced by alternative splicing.

Format

Whole serum

Clonality

Polyclonal

Isotype

Mixed

Applications

IHC, WB

Host Species

Rabbit

Immunogen

A synthetic peptide (PRVEKTPSLPDDLSD) as a part of human GFR alpha-2 protein (aa: 376-390) conjugated to KLH.

Immunogen Species

Human

Species Reactivity

Human, Rat

Storage

Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material. After reconstitution keep aliquots at -20°C for a higher stability, and at 2-8°C with an appropriate antibacterial agent. Glycerol (1:1) may be added for an additional stability. Avoid repetitive freeze/thaw cycles.

Physical State

Lyophilized

Dilution Ranges

WB: 1:500-1:1000
IHC: 1:500-1:1000

Application Details

This antibody stains the large neurons in the rat DRG. This antibody also is ideal for WB analysis of rat DRG and brain homogenate.

Conjugate

Unconjugated

Specificity

Western blot analysis indicates a high level of specificity to GFR alpha-2 for this antiserum. This antibody is known to react with rat GFR alpha-2 and from IHC analysis, there appears to be no cross-reactivity with other members of the GFR family.

Usage Statement

For research use only.

Country of Origin

United States

Expiration

12 months after date of receipt (unopened vial).

Synonyms

GDNF family receptor alpha-2; GFR-alpha-2; Neurturin receptor alpha; NTNR-alpha; NRTNR-alpha; TGF-beta-related neurotrophic factor receptor 2; GDNF receptor beta; GDNFR-beta; RET ligand 2

UniProt ID

O00451

Shipping

25°C (ambient)

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Anti-GFR alpha-2 Antibody

SKU: R-067-100

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