Anti-Gelsolin Antibody (20)
Our mouse Gelsolin monoclonal antibody from Antibodies Incorporated is produced in-house from clone 20. It detects human Gelsolin and is Protein A or Protein G purified. Works in ELISA, IF, IHC, WB.
Immunofluorescent staining of Gelsolin in human cell line U-251 MG using Anti-Gelsolin Antibody (Cat. ABS 017-20-010). Cells where fixed with formaldehyde and permeabilized prior to staining Primary antibody (ABS 017-20-010) was incubated with the cells at a dilution of 1:2000.
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SKU: ABS 017-20-010
Ships: 1-2 business days
Product Details
Gelsolin
Gelsolin participates in the extracellular actin scavenger system, binding actin and disaggregating filamentous actin released from dying cells. Actin monomers are then transferred to Gc-globulin. The plasma concentration of gelsolin is reduced in conditions of major actin release, such as acute liver failure, major trauma and rhabdomyolysis, where multi-organ failure is a risk. It has been suggested that gelsolin, like Gc-globulin, can be a prognostic factor in these conditions.
Protein A or Protein G purified
1 mg/mL ±15%
Monoclonal
20
IgG1/k
ELISA, IF, IHC, WB
Mouse
GSN
83 kDa
Gelsolin purified from human plasma
Human
Human
2-8°C without exposure to light
Liquid
BSA free
0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide
IHC: 1:6000
ICC: 1:2000
ICC: 1:2000
ABS 017-20 does not work as a capture antibody in sandwich ELISA.
Unconjugated
ABS 017-20 binds human gelsolin.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
United States
24 months from date of receipt
GSN, ADF, AGEL, AMYLD4, gelsolin, actin-depolymerizing factor, brevin, epididymis secretory sperm binding protein
2934
Shipped on ice packs

