Anti-Exendin-4 Antibody (35)

Name: Anti-Exendin-4 Antibody
Brand: Antibodies Incorporated
SKU: ABS 012-35-010
Price: 450.0 USD
Availability: InStock

Our mouse Exendin-4 monoclonal antibody from Antibodies Incorporated is produced in-house from clone 35. It detects gila monster heloderma suspectum Exendin-4 and is Protein A or Protein G purified. Works in ELISA.

Anti-Exendin-4 Antibody

Click on image to zoom

Species Reactivity

Lizard

Applications

ELISA

Host Species

Mouse

Go to Full Product Details

Data Sheet

SKU: ABS 012-35-010

Volume: 100 uL

Variant

Price:

$450.00

Quantity:

Ships: 1-2 business days

Product Details

Target

Exendin-4

Scientific Background

Exendin-4 is a 39 amino acid peptide found in venom from the Gila monster Heloderma suspectum. It is a member of the glucagon-secretin family of peptide hormones and neuropeptides. Exendin-4 is a potent agonist of the GLP-1 receptor and hence a potent stimulator of insulin secretion.

Format

Protein A or Protein G purified

Concentration

1 mg/mL ±15%

Clonality

Monoclonal

Clone

Isotype

IgG1/k

Applications

ELISA

Host Species

Mouse

Gene Name

N/A

Molecular Weight

4.2 kDa

Immunogen

Synthetic exendin-4

Immunogen Species

Gila monster Heloderma suspectum

Species Reactivity

Lizard

Storage

2-8°C without exposure to light

Physical State

Liquid

Production Notes

BSA free

Buffer

0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide

Application Details

ABS 012-35 binds to exendin-4 when coated on ELISA wells and reacts specifically with exendin-4 in solution giving a Ka of 1.1x10E9 in an inhibition ELISA. The binding between ABS 012-35 and exendin-4 is disrupted by 4.5 M MgCl2. ABS 012-35 (as biotinylated detection antibody) forms a sandwich ELISA pair with ABS 033-10 (as capture antibody) for measuring exendin-4, giving a detection limit of as little as 40 pmol/L in an unoptimized buffer assay. (1)

Conjugate

Unconjugated

Specificity

Specific for exendin-4. No cross-reactivity with GLP-1, GLP-2 (human) or glucagon coated on ELISA wells. The epitope is in the 9-39 region of the peptide, and the antibody cross-reacts strongly with exendin (9-39) amide.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Synonyms

Exenatide

UniProt ID

P26349

NCBI Gene ID

Shipping

Shipped on ice packs

Recover password

Create my account

Anti-Exendin-4 Antibody (35)

SKU: ABS 012-35-010

Product Details

Bulk Order Anti-Exendin-4 Antibody

Related Products

Recently Viewed