Our mouse Complement C3 monoclonal antibody from Antibodies Incorporated is produced in-house from clone F1-8. It detects human Complement C3 and is Protein A or Protein G purified. Works in ELISA, IP, IAP.
C3 is a central component of the complement system, consisting of a beta-chain (75 kDa) and an alpha-chain (110 kDa) connected by cystein bridges. Cleavage of C3 into C3b (177 kDa) and C3a (9 kDa) is a pivotal step in the complement activation cascade, which can be initiated by three distinct pathways—the classical, the lectin and the alternative complement pathway.
Protein A or Protein G purified
1 mg/mL ±15%
Monoclonal
F1-8
IgG1/k
ELISA
Mouse
C3
beta-chain (75 kDa) and an alpha-chain (110 kDa)
Complement component 3 (C3) purified from human plasma.
Human
Human
2-8°C without exposure to light
Liquid
BSA free
0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide
CAM 008-01 was used in ELISA. (1)
Unconjugated
CAM 008-01 is specific for human complement component 3 (C3/C3b/C3c). The antibody CAM 008-01 reacts with the 75 kd beta-chain of the human complement factor 3.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
United States
24 months from date of receipt
C3, AHUS5, ARMD9, ASP, C3a, C3b, CPAMD1, HEL-S-62p, complement C3, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1, C3a anaphylatoxin, acylation-stimulating protein cleavage product, complement component 3, complement component C3a, complement component C3b, epididymis secretory sperm binding protein Li 62p, prepro-C3
